Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/-
Location 1585550..1586803 Replicon chromosome
Accession NZ_CP127228
Organism Pseudomonas tohonis strain KRS022

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag QQ016_RS06980 Protein ID WP_285961956.1
Coordinates 1585550..1586134 (-) Length 195 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag QQ016_RS06985 Protein ID WP_285961957.1
Coordinates 1586246..1586803 (-) Length 186 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QQ016_RS06945 1580635..1581591 - 957 WP_173174505.1 helix-turn-helix domain-containing protein -
QQ016_RS06950 1581820..1582371 + 552 WP_285961951.1 chalcone isomerase family protein -
QQ016_RS06955 1582383..1582919 + 537 WP_285961952.1 DUF3833 domain-containing protein -
QQ016_RS06960 1582950..1583255 + 306 WP_285961953.1 DUF6482 family protein -
QQ016_RS06965 1583252..1584793 + 1542 WP_285961954.1 cryptochrome/photolyase family protein -
QQ016_RS06970 1584790..1584930 + 141 WP_111261604.1 DUF2256 domain-containing protein -
QQ016_RS06975 1584956..1585339 - 384 WP_285961955.1 cytochrome c -
QQ016_RS06980 1585550..1586134 - 585 WP_285961956.1 HD domain-containing protein Toxin
QQ016_RS06985 1586246..1586803 - 558 WP_285961957.1 helix-turn-helix transcriptional regulator Antitoxin
QQ016_RS06990 1587059..1587574 + 516 WP_285961958.1 thioredoxin family protein -
QQ016_RS06995 1587601..1588350 - 750 WP_285961959.1 NAD-dependent deacylase -
QQ016_RS07000 1588535..1590622 + 2088 WP_263153892.1 PAS domain S-box protein -
QQ016_RS07005 1590625..1591236 - 612 WP_285961960.1 LysE family transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

5'-deoxynucleotidase YfbR/HDDC2

(8-189)

Antitoxin

Cro/C1-type helix-turn-helix domain

(12-67)


Sequences

Toxin        


Download         Length: 195 a.a.        Molecular weight: 21669.38 Da        Isoelectric Point: 4.6874

>T283628 WP_285961956.1 NZ_CP127228:c1586134-1585550 [Pseudomonas tohonis]
MNIDIIRARLDFLREAERLKDVLRSAHTSSGRAESTAEHSWRLCLMAITFADELAGLDLLRVLKMCVVHDLGEAIHGDIP
AVEQGGHPDKGAQEREDLLTLTRTLDDGLRGEILALWDDYENAASPEALAVKALDKLETLLQHTQGANPEDFDYAFNLGY
GRRYTSGEPLFAAIRAQLDEDTRRRMEAQASVPR

Download         Length: 585 bp

Antitoxin


Download         Length: 186 a.a.        Molecular weight: 20306.40 Da        Isoelectric Point: 8.3150

>AT283628 WP_285961957.1 NZ_CP127228:c1586803-1586246 [Pseudomonas tohonis]
MHDSLPKPVSLGLALRRWRLLHRVKQAHAAQLFGVAQSTISRWESGAQAMEPAERARVEQVLGARLEAAADQALARLVGD
SPRAVHLVCDLSHRLLACSALRAAEFSVPLSELLGRSLWRYATPEIVRQEDALDALGWRDVLMPPALEFGSGSNESAIVP
IRQGLCRWTRMTLSDGTAARLVETL

Download         Length: 558 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References