Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | vapBC/- |
| Location | 1585550..1586803 | Replicon | chromosome |
| Accession | NZ_CP127228 | ||
| Organism | Pseudomonas tohonis strain KRS022 | ||
Toxin (Protein)
| Gene name | vapC | Uniprot ID | - |
| Locus tag | QQ016_RS06980 | Protein ID | WP_285961956.1 |
| Coordinates | 1585550..1586134 (-) | Length | 195 a.a. |
Antitoxin (Protein)
| Gene name | vapB | Uniprot ID | - |
| Locus tag | QQ016_RS06985 | Protein ID | WP_285961957.1 |
| Coordinates | 1586246..1586803 (-) | Length | 186 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| QQ016_RS06945 | 1580635..1581591 | - | 957 | WP_173174505.1 | helix-turn-helix domain-containing protein | - |
| QQ016_RS06950 | 1581820..1582371 | + | 552 | WP_285961951.1 | chalcone isomerase family protein | - |
| QQ016_RS06955 | 1582383..1582919 | + | 537 | WP_285961952.1 | DUF3833 domain-containing protein | - |
| QQ016_RS06960 | 1582950..1583255 | + | 306 | WP_285961953.1 | DUF6482 family protein | - |
| QQ016_RS06965 | 1583252..1584793 | + | 1542 | WP_285961954.1 | cryptochrome/photolyase family protein | - |
| QQ016_RS06970 | 1584790..1584930 | + | 141 | WP_111261604.1 | DUF2256 domain-containing protein | - |
| QQ016_RS06975 | 1584956..1585339 | - | 384 | WP_285961955.1 | cytochrome c | - |
| QQ016_RS06980 | 1585550..1586134 | - | 585 | WP_285961956.1 | HD domain-containing protein | Toxin |
| QQ016_RS06985 | 1586246..1586803 | - | 558 | WP_285961957.1 | helix-turn-helix transcriptional regulator | Antitoxin |
| QQ016_RS06990 | 1587059..1587574 | + | 516 | WP_285961958.1 | thioredoxin family protein | - |
| QQ016_RS06995 | 1587601..1588350 | - | 750 | WP_285961959.1 | NAD-dependent deacylase | - |
| QQ016_RS07000 | 1588535..1590622 | + | 2088 | WP_263153892.1 | PAS domain S-box protein | - |
| QQ016_RS07005 | 1590625..1591236 | - | 612 | WP_285961960.1 | LysE family transporter | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 195 a.a. Molecular weight: 21669.38 Da Isoelectric Point: 4.6874
>T283628 WP_285961956.1 NZ_CP127228:c1586134-1585550 [Pseudomonas tohonis]
MNIDIIRARLDFLREAERLKDVLRSAHTSSGRAESTAEHSWRLCLMAITFADELAGLDLLRVLKMCVVHDLGEAIHGDIP
AVEQGGHPDKGAQEREDLLTLTRTLDDGLRGEILALWDDYENAASPEALAVKALDKLETLLQHTQGANPEDFDYAFNLGY
GRRYTSGEPLFAAIRAQLDEDTRRRMEAQASVPR
MNIDIIRARLDFLREAERLKDVLRSAHTSSGRAESTAEHSWRLCLMAITFADELAGLDLLRVLKMCVVHDLGEAIHGDIP
AVEQGGHPDKGAQEREDLLTLTRTLDDGLRGEILALWDDYENAASPEALAVKALDKLETLLQHTQGANPEDFDYAFNLGY
GRRYTSGEPLFAAIRAQLDEDTRRRMEAQASVPR
Download Length: 585 bp
Antitoxin
Download Length: 186 a.a. Molecular weight: 20306.40 Da Isoelectric Point: 8.3150
>AT283628 WP_285961957.1 NZ_CP127228:c1586803-1586246 [Pseudomonas tohonis]
MHDSLPKPVSLGLALRRWRLLHRVKQAHAAQLFGVAQSTISRWESGAQAMEPAERARVEQVLGARLEAAADQALARLVGD
SPRAVHLVCDLSHRLLACSALRAAEFSVPLSELLGRSLWRYATPEIVRQEDALDALGWRDVLMPPALEFGSGSNESAIVP
IRQGLCRWTRMTLSDGTAARLVETL
MHDSLPKPVSLGLALRRWRLLHRVKQAHAAQLFGVAQSTISRWESGAQAMEPAERARVEQVLGARLEAAADQALARLVGD
SPRAVHLVCDLSHRLLACSALRAAEFSVPLSELLGRSLWRYATPEIVRQEDALDALGWRDVLMPPALEFGSGSNESAIVP
IRQGLCRWTRMTLSDGTAARLVETL
Download Length: 558 bp
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|
Antitoxin
| Source | ID | Structure |
|---|