Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN-MazE
Location 285706..286339 Replicon chromosome
Accession NZ_CP127228
Organism Pseudomonas tohonis strain KRS022

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag QQ016_RS01370 Protein ID WP_285961366.1
Coordinates 285968..286339 (+) Length 124 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag QQ016_RS01365 Protein ID WP_285961365.1
Coordinates 285706..285942 (+) Length 79 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QQ016_RS01340 281452..281808 - 357 WP_173180260.1 hydroxyisourate hydrolase -
QQ016_RS01345 281805..282311 - 507 WP_285961361.1 nucleoside deaminase -
QQ016_RS01350 282351..283688 - 1338 WP_285961362.1 nucleobase:cation symporter-2 family protein -
QQ016_RS01355 283847..284761 + 915 WP_285961363.1 LysR family transcriptional regulator -
QQ016_RS01360 284934..285566 - 633 WP_285961364.1 hypothetical protein -
QQ016_RS01365 285706..285942 + 237 WP_285961365.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
QQ016_RS01370 285968..286339 + 372 WP_285961366.1 PIN domain-containing protein Toxin
QQ016_RS01375 286348..287115 - 768 WP_285961367.1 DUF2092 domain-containing protein -
QQ016_RS01380 287240..288136 + 897 WP_285961368.1 alpha/beta hydrolase -
QQ016_RS01385 288210..288806 + 597 WP_263150039.1 chalcone isomerase family protein -
QQ016_RS01390 288814..289278 - 465 WP_285961369.1 DoxX family protein -
QQ016_RS01395 289292..290077 - 786 WP_285961370.1 DNA-binding domain-containing protein -
QQ016_RS01400 290074..290913 - 840 WP_285961371.1 DUF692 domain-containing protein -
QQ016_RS01405 290930..291202 - 273 WP_021217973.1 DUF2282 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(1-105)

Antitoxin

SpoVT-AbrB domain

(5-45)


Sequences

Toxin        


Download         Length: 124 a.a.        Molecular weight: 13568.81 Da        Isoelectric Point: 7.1892

>T283627 WP_285961366.1 NZ_CP127228:285968-286339 [Pseudomonas tohonis]
VLLYLLSADPAKADAAEALLAKRPTISVQVLNEVASVCSRKLRMSWDEIGRFLELVQGFCRVVPVTLEIHRQARELAERY
RLSFYDACIAAAALVAGCSTLHSEDMHSGLLIDGRLRVLNPFG

Download         Length: 372 bp

Antitoxin


Download         Length: 79 a.a.        Molecular weight: 8799.93 Da        Isoelectric Point: 4.6838

>AT283627 WP_285961365.1 NZ_CP127228:285706-285942 [Pseudomonas tohonis]
MQVAKWGNSLAVRIPASVVEALELKEGDDIEILIEGDRTFAISKKPDDEARLARLRAFRGKLPADFRFNRDEDAGRED

Download         Length: 237 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References