283624

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) spoIISABC/SpoIISA-SpoIISB
Location 1381796..1382715 Replicon chromosome
Accession NZ_CP127223
Organism Bacillus licheniformis strain Jrh14-10

Toxin (Protein)


Gene name spoIISA Uniprot ID T5HIF3
Locus tag QQ984_RS07095 Protein ID WP_003180879.1
Coordinates 1381969..1382715 (-) Length 249 a.a.

Antitoxin (Protein)


Gene name spoIISB Uniprot ID T5HT37
Locus tag QQ984_RS07090 Protein ID WP_003180877.1
Coordinates 1381796..1381969 (-) Length 58 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QQ984_RS07065 (QQ984_07065) 1377221..1378318 + 1098 WP_003180867.1 mannonate dehydratase -
QQ984_RS07070 (QQ984_07070) 1378294..1379142 + 849 WP_003180869.1 SDR family oxidoreductase -
QQ984_RS07075 (QQ984_07075) 1379169..1380182 + 1014 WP_011197810.1 zinc-binding alcohol dehydrogenase family protein -
QQ984_RS07080 (QQ984_07080) 1380235..1381506 + 1272 WP_009328725.1 MFS transporter -
QQ984_RS07085 (QQ984_07085) 1381569..1381700 - 132 WP_003180875.1 hypothetical protein -
QQ984_RS07090 (QQ984_07090) 1381796..1381969 - 174 WP_003180877.1 type II toxin-antitoxin system SpoIISB family antitoxin Antitoxin
QQ984_RS07095 (QQ984_07095) 1381969..1382715 - 747 WP_003180879.1 type II toxin-antitoxin system SpoIISA family toxin Toxin
QQ984_RS07100 (QQ984_07100) 1382826..1383824 - 999 WP_009328723.1 inorganic phosphate transporter -
QQ984_RS07105 (QQ984_07105) 1383837..1384454 - 618 WP_003180884.1 DUF47 domain-containing protein -
QQ984_RS07110 (QQ984_07110) 1384786..1386543 + 1758 WP_011197813.1 gamma-glutamyltransferase -
QQ984_RS07115 (QQ984_07115) 1386672..1387315 + 644 Protein_1348 DUF624 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin SpoIISA, type II toxin-antitoxin system

(3-238)

Antitoxin

Antitoxin SpoIISB

(1-57)


Sequences

Toxin        


Download         Length: 249 a.a.        Molecular weight: 29391.80 Da        Isoelectric Point: 4.5367

>T283624 WP_003180879.1 NZ_CP127223:c1382715-1381969 [Bacillus licheniformis]
MLLFYQFLVWLIVLALALYVAAVWRFEKQLAEKTVAIRKTWYLLYVIGAVIYWTHDPQSIFTNPLHYLIVAVFFTLTDAF
IFLNAYFKKLGSSELATDTRMLLEENNDLLHTYQNRLKTFQYLLKNEPIHIYYGNIEAYAEGIEKLIKRFAEKMNISAAL
CEYNSEESKDHLLEHMENRFDVQEKLDRKDVYYEENGKMVLIPFSIHDFDYVMKLTSEDLVTEFDYLLFTSLTSIYDLLL
PNEEEGDD

Download         Length: 747 bp

Antitoxin


Download         Length: 58 a.a.        Molecular weight: 6945.04 Da        Isoelectric Point: 10.9186

>AT283624 WP_003180877.1 NZ_CP127223:c1381969-1381796 [Bacillus licheniformis]
MEPAFQQDQESVKKRLAFKMFKRQSKTNIAKYEVSPHTERIFRQNERLIGEYKRKKA

Download         Length: 174 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB T5HIF3

Antitoxin

Source ID Structure
AlphaFold DB T5HT37

References