Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yoeB-relB/YoeB-YefM
Location 3554677..3555183 Replicon chromosome
Accession NZ_CP127168
Organism Glutamicibacter nicotianae strain AT6

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag QQS42_RS16875 Protein ID WP_128470932.1
Coordinates 3554929..3555183 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A4Y3VX22
Locus tag QQS42_RS16870 Protein ID WP_038992858.1
Coordinates 3554677..3554928 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QQS42_RS16850 (QQS42_16850) 3550255..3551493 + 1239 WP_052253958.1 CoA transferase -
QQS42_RS16855 (QQS42_16855) 3551549..3551905 + 357 WP_198934360.1 thioesterase family protein -
QQS42_RS16860 (QQS42_16860) 3551915..3553129 + 1215 WP_073707123.1 acyl-CoA dehydrogenase family protein -
QQS42_RS16865 (QQS42_16865) 3553266..3554321 + 1056 WP_073707124.1 GTP-binding protein -
QQS42_RS16870 (QQS42_16870) 3554677..3554928 + 252 WP_038992858.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
QQS42_RS16875 (QQS42_16875) 3554929..3555183 + 255 WP_128470932.1 Txe/YoeB family addiction module toxin Toxin
QQS42_RS16880 (QQS42_16880) 3555251..3555720 + 470 Protein_3290 DUF2220 family protein -
QQS42_RS16885 (QQS42_16885) 3556522..3557358 - 837 WP_285675056.1 bifunctional allantoicase/(S)-ureidoglycine aminohydrolase -
QQS42_RS16890 (QQS42_16890) 3557369..3558622 - 1254 WP_073707128.1 aldolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(2-69)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 9996.39 Da        Isoelectric Point: 7.2749

>T283607 WP_128470932.1 NZ_CP127168:3554929-3555183 [Glutamicibacter nicotianae]
VRLVWDRAGWDDYVHWQTADRRVLKRVNTLIEACLPDPFQGIGKPEQLKYGASGSWSRRITDEHRLVYIVIEEDLIILQA
RYHY

Download         Length: 255 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9459.51 Da        Isoelectric Point: 4.4805

>AT283607 WP_038992858.1 NZ_CP127168:3554677-3554928 [Glutamicibacter nicotianae]
MSISASEARKTLFPLIEQVNDDRQAVEIVSRKGNAVLMAADEYAAWQETAYLFRSPANARRLLDAYERARSGITETHELD
WDE

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A4Y3VX22

References