Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/MazF(toxin)
Location 1124444..1125079 Replicon chromosome
Accession NZ_CP127162
Organism Paenibacillus sp. C31

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag QPK24_RS05345 Protein ID WP_160032284.1
Coordinates 1124729..1125079 (+) Length 117 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag QPK24_RS05340 Protein ID WP_160032285.1
Coordinates 1124444..1124725 (+) Length 94 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QPK24_RS05325 (QPK24_05325) 1120872..1121435 + 564 WP_285746797.1 GbsR/MarR family transcriptional regulator -
QPK24_RS05330 (QPK24_05330) 1121611..1122792 + 1182 WP_285746799.1 outer membrane lipoprotein carrier protein LolA -
QPK24_RS05335 (QPK24_05335) 1123042..1124223 + 1182 WP_285746802.1 alanine racemase -
QPK24_RS05340 (QPK24_05340) 1124444..1124725 + 282 WP_160032285.1 ribbon-helix-helix protein, CopG family Antitoxin
QPK24_RS05345 (QPK24_05345) 1124729..1125079 + 351 WP_160032284.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
QPK24_RS05350 (QPK24_05350) 1125314..1127503 + 2190 WP_285746804.1 alpha-galactosidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(4-111)

Antitoxin

Ribbon-helix-helix protein, CopG

(9-45)


Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 12824.75 Da        Isoelectric Point: 4.8502

>T283604 WP_160032284.1 NZ_CP127162:1124729-1125079 [Paenibacillus sp. C31]
MIVKRGDVFFADLSPVVGSEQGGVRPVLVIQNDIGNRFSPTCIVAAITAQIQKAKLPTHVEIDAEAHGFDRDSVVLLEQI
RTIDKQRLTDKITHLDDETMKLVNESLQISLGLIDF

Download         Length: 351 bp

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10769.46 Da        Isoelectric Point: 7.2024

>AT283604 WP_160032285.1 NZ_CP127162:1124444-1124725 [Paenibacillus sp. C31]
MTNVQNTKRIMISLPDHLLQEVDGIVAMENSNRSEFIRQAMKLYLMERKKRYIRETMQRGYMEMAKINLTMASEAFHAED
DADSTLGRLVSGV

Download         Length: 282 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References