Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/MazF(toxin)
Location 1460200..1460828 Replicon chromosome
Accession NZ_CP127161
Organism Proteiniborus sp. MB09-C3

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag QO263_RS07045 Protein ID WP_285629230.1
Coordinates 1460478..1460828 (+) Length 117 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag QO263_RS07040 Protein ID WP_285628093.1
Coordinates 1460200..1460481 (+) Length 94 a.a.

Genomic Context

QO263_RS07015QO263_RS07020QO263_RS07025QO263_RS07030QO263_RS07035QO263_RS07040QO263_RS07045QO263_RS07050QO263_RS07055QO263_RS07060QO263_RS07065QO263_RS07070QO263_RS07075
Location: 1455720..1456328 (609 bp)
Type: Others
Protein ID: WP_285628079.1
Location: 1456442..1456708 (267 bp)
Type: Others
Protein ID: WP_285628082.1
Location: 1456743..1458038 (1296 bp)
Type: Others
Protein ID: WP_285628085.1
Location: 1458068..1458721 (654 bp)
Type: Others
Protein ID: WP_285628088.1
Location: 1458869..1460041 (1173 bp)
Type: Others
Protein ID: WP_285628091.1
Location: 1460200..1460481 (282 bp)
Type: Antitoxin
Protein ID: WP_285628093.1
Location: 1460478..1460828 (351 bp)
Type: Toxin
Protein ID: WP_285629230.1
Location: 1461058..1461606 (549 bp)
Type: Others
Protein ID: WP_285628096.1
Location: 1461715..1462803 (1089 bp)
Type: Others
Protein ID: WP_285628099.1
Location: 1462865..1464004 (1140 bp)
Type: Others
Protein ID: WP_285628102.1
Location: 1463994..1464455 (462 bp)
Type: Others
Protein ID: WP_285628105.1
Location: 1464472..1464963 (492 bp)
Type: Others
Protein ID: WP_285628108.1
Location: 1464968..1465510 (543 bp)
Type: Others
Protein ID: WP_285628110.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
QO263_RS07015 (QO263_07015)1455720..1456328+609WP_285628079.1hypothetical protein-
QO263_RS07020 (QO263_07020)1456442..1456708+267WP_285628082.1hypothetical protein-
QO263_RS07025 (QO263_07025)1456743..1458038+1296WP_285628085.1NAD(P)H-hydrate dehydratase-
QO263_RS07030 (QO263_07030)1458068..1458721+654WP_285628088.1outer membrane lipoprotein-sorting protein-
QO263_RS07035 (QO263_07035)1458869..1460041+1173WP_285628091.1alanine racemase-
QO263_RS07040 (QO263_07040)1460200..1460481+282WP_285628093.1ribbon-helix-helix protein, CopG familyAntitoxin
QO263_RS07045 (QO263_07045)1460478..1460828+351WP_285629230.1type II toxin-antitoxin system PemK/MazF family toxinToxin
QO263_RS07050 (QO263_07050)1461058..1461606+549WP_285628096.1hypothetical protein-
QO263_RS07055 (QO263_07055)1461715..1462803+1089WP_285628099.1glycosyltransferase-
QO263_RS07060 (QO263_07060)1462865..1464004+1140WP_285628102.1glycosyltransferase family 4 protein-
QO263_RS07065 (QO263_07065)1463994..1464455+462WP_285628105.1DUF4330 domain-containing protein-
QO263_RS07070 (QO263_07070)1464472..1464963+492WP_285628108.1DUF4330 domain-containing protein-
QO263_RS07075 (QO263_07075)1464968..1465510+543WP_285628110.1hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(2-113)

Antitoxin

Ribbon-helix-helix protein, CopG

(6-43)


Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 12830.92 Da        Isoelectric Point: 6.4646

>T283603 WP_285629230.1 NZ_CP127161:1460478-1460828 [Proteiniborus sp. MB09-C3]
VIVKRGDILYADLSPVIGSEQGGVRPVLVIQNDIGNKYSPTVIISAITSQINKAKLPTHIEITAPEYGLPKDSVVLLEQI
RTIDKKRLREKIGHFDDDMMAKVDECLKISIGLSDY

Download         Length: 351 bp

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 11258.99 Da        Isoelectric Point: 4.9930

>AT283603 WP_285628093.1 NZ_CP127161:1460200-1460481 [Proteiniborus sp. MB09-C3]
MAETKRIMISLPNSLLEEVDNIVSMESKNRSEFIREAMKLYLRERKKIQLKEVMKNGYREMSQINLYFAEMGIEEDYNEL
IKYESRLTGREEW

Download         Length: 282 bp


Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References