Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/MazF(toxin)
Location 1460200..1460828 Replicon chromosome
Accession NZ_CP127161
Organism Proteiniborus sp. MB09-C3

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag QO263_RS07045 Protein ID WP_285629230.1
Coordinates 1460478..1460828 (+) Length 117 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag QO263_RS07040 Protein ID WP_285628093.1
Coordinates 1460200..1460481 (+) Length 94 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QO263_RS07015 (QO263_07015) 1455720..1456328 + 609 WP_285628079.1 hypothetical protein -
QO263_RS07020 (QO263_07020) 1456442..1456708 + 267 WP_285628082.1 hypothetical protein -
QO263_RS07025 (QO263_07025) 1456743..1458038 + 1296 WP_285628085.1 NAD(P)H-hydrate dehydratase -
QO263_RS07030 (QO263_07030) 1458068..1458721 + 654 WP_285628088.1 outer membrane lipoprotein-sorting protein -
QO263_RS07035 (QO263_07035) 1458869..1460041 + 1173 WP_285628091.1 alanine racemase -
QO263_RS07040 (QO263_07040) 1460200..1460481 + 282 WP_285628093.1 ribbon-helix-helix protein, CopG family Antitoxin
QO263_RS07045 (QO263_07045) 1460478..1460828 + 351 WP_285629230.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
QO263_RS07050 (QO263_07050) 1461058..1461606 + 549 WP_285628096.1 hypothetical protein -
QO263_RS07055 (QO263_07055) 1461715..1462803 + 1089 WP_285628099.1 glycosyltransferase -
QO263_RS07060 (QO263_07060) 1462865..1464004 + 1140 WP_285628102.1 glycosyltransferase family 4 protein -
QO263_RS07065 (QO263_07065) 1463994..1464455 + 462 WP_285628105.1 DUF4330 domain-containing protein -
QO263_RS07070 (QO263_07070) 1464472..1464963 + 492 WP_285628108.1 DUF4330 domain-containing protein -
QO263_RS07075 (QO263_07075) 1464968..1465510 + 543 WP_285628110.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(2-113)

Antitoxin

Ribbon-helix-helix protein, CopG

(6-43)


Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 12830.92 Da        Isoelectric Point: 6.4646

>T283603 WP_285629230.1 NZ_CP127161:1460478-1460828 [Proteiniborus sp. MB09-C3]
VIVKRGDILYADLSPVIGSEQGGVRPVLVIQNDIGNKYSPTVIISAITSQINKAKLPTHIEITAPEYGLPKDSVVLLEQI
RTIDKKRLREKIGHFDDDMMAKVDECLKISIGLSDY

Download         Length: 351 bp

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 11258.99 Da        Isoelectric Point: 4.9930

>AT283603 WP_285628093.1 NZ_CP127161:1460200-1460481 [Proteiniborus sp. MB09-C3]
MAETKRIMISLPNSLLEEVDNIVSMESKNRSEFIREAMKLYLRERKKIQLKEVMKNGYREMSQINLYFAEMGIEEDYNEL
IKYESRLTGREEW

Download         Length: 282 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References