Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/Txe-RelB
Location 474149..474678 Replicon chromosome
Accession NZ_CP127160
Organism Enterococcus sp. FZMF

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag QN079_RS02260 Protein ID WP_087626849.1
Coordinates 474412..474678 (+) Length 89 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID A0A377KQM1
Locus tag QN079_RS02255 Protein ID WP_010748737.1
Coordinates 474149..474412 (+) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QN079_RS02240 (QN079_02240) 469721..470983 - 1263 WP_289230359.1 glycoside hydrolase family 27 protein -
QN079_RS02245 (QN079_02245) 471104..472003 + 900 WP_081116191.1 AraC family transcriptional regulator -
QN079_RS02250 (QN079_02250) 472054..473994 + 1941 WP_289230360.1 glycoside hydrolase family 127 protein -
QN079_RS02255 (QN079_02255) 474149..474412 + 264 WP_010748737.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
QN079_RS02260 (QN079_02260) 474412..474678 + 267 WP_087626849.1 Txe/YoeB family addiction module toxin Toxin
QN079_RS02265 (QN079_02265) 474871..477702 + 2832 WP_289230361.1 discoidin domain-containing protein -
QN079_RS02270 (QN079_02270) 477834..478496 - 663 WP_005227316.1 ABC transporter permease -
QN079_RS02275 (QN079_02275) 478501..479421 - 921 WP_005227318.1 osmoprotectant ABC transporter substrate-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(9-87)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(5-69)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10612.14 Da        Isoelectric Point: 10.3322

>T283600 WP_087626849.1 NZ_CP127160:474412-474678 [Enterococcus sp. FZMF]
MRSDTVTIKNSAKVDLRKIKQSNLKKQFEEVIQALKEDPYMPTQSFEKLRPTHEGRYSRRLSRQHRVVYKVDEKNKVVEI
YSAWTHYE

Download         Length: 267 bp

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9958.03 Da        Isoelectric Point: 4.2682

>AT283600 WP_010748737.1 NZ_CP127160:474149-474412 [Enterococcus sp. FZMF]
MAKTTMNPSTARKNFYQLLKDVNENHTEIEIISDRSGNNAVLIGLGDWRAIQETLFLEQTGTLEKVRDREKDDSGFTDID
DIDWQAL

Download         Length: 264 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A377KQM1

References