Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2008136..2008281 Replicon chromosome
Accession NZ_CP127153
Organism Klebsiella pneumoniae subsp. pneumoniae strain T1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2008172..2008274 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2008136..2008281 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QP513_RS09865 (QP513_09865) 2003266..2005326 + 2061 WP_004151449.1 oligopeptidase B -
QP513_RS09870 (QP513_09870) 2005330..2005989 - 660 WP_002911407.1 exodeoxyribonuclease X -
QP513_RS09875 (QP513_09875) 2006068..2006298 - 231 WP_002911406.1 DNA polymerase III subunit theta -
QP513_RS09880 (QP513_09880) 2006411..2006785 + 375 WP_004151448.1 CopC domain-containing protein YobA -
QP513_RS09885 (QP513_09885) 2006789..2007658 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
QP513_RS09890 (QP513_09890) 2007675..2008013 + 339 WP_002911404.1 YebY family protein -
- 2008136..2008281 - 146 - - Antitoxin
- 2008172..2008274 + 103 - - Toxin
QP513_RS09895 (QP513_09895) 2008649..2008792 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
QP513_RS09900 (QP513_09900) 2008897..2009865 - 969 WP_004151446.1 VirK/YbjX family protein -
QP513_RS09905 (QP513_09905) 2010022..2010675 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
QP513_RS09910 (QP513_09910) 2010672..2010863 - 192 WP_002911395.1 YebW family protein -
QP513_RS09915 (QP513_09915) 2010961..2011200 - 240 WP_002911393.1 YebV family protein -
QP513_RS09920 (QP513_09920) 2011316..2012749 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T283580 NZ_CP127153:2008172-2008274 [Klebsiella pneumoniae subsp. pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT283580 NZ_CP127153:c2008281-2008136 [Klebsiella pneumoniae subsp. pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References