Detailed information of TA system TA283571

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): PanAT/DUF4065(antitoxin)
• Location: 278094..279049
• Replicon: chromosome
• Accession: NZ_CP127126
• Organism: Pseudomonas aeruginosa PA14 strain MA3 isolate DTU_MIE

Toxin (Protein)

• Gene name: panT
• Uniprot ID: -
• Locus tag: P4A98_RS01285
• Protein ID: WP_170868735.1
• Coordinates: 278723..279049 (+)
• Length: 109 a.a.

Antitoxin (Protein)

• Gene name: panA
• Uniprot ID: -
• Locus tag: P4A98_RS01280
• Protein ID: WP_023107584.1
• Coordinates: 278094..278651 (+)
• Length: 186 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
P4A98_RS01255 (P4A98_01255)	273151..273438	-	288	WP_003137130.1	hypothetical protein	-
P4A98_RS01260 (P4A98_01260)	273530..274006	-	477	WP_003118626.1	MarR family transcriptional regulator	-
P4A98_RS01265 (P4A98_01265)	274047..275537	-	1491	WP_003137133.1	UbiD family decarboxylase HudA	-
P4A98_RS01270 (P4A98_01270)	275671..276357	-	687	WP_003106170.1	YoaK family protein	-
P4A98_RS01275 (P4A98_01275)	276521..277453	-	933	WP_003084116.1	hypothetical protein	-
P4A98_RS01280 (P4A98_01280)	278094..278651	+	558	WP_023107584.1	Panacea domain-containing protein	Antitoxin
P4A98_RS01285 (P4A98_01285)	278723..279049	+	327	WP_170868735.1	hypothetical protein	Toxin
P4A98_RS01295 (P4A98_01295)	280491..282083	-	1593	WP_277424738.1	DUF2875 family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

• Antitoxin SocA-like, Panacea domain (28-138)

Sequences

Toxin

Protein

• Length: 109 a.a.
• Molecular weight: 12385.38 Da
• Isoelectric Point: 9.1081

>T283571 WP_170868735.1 NZ_CP127126:278723-279049 [Pseudomonas aeruginosa PA14]
MNDPVYCPVLGYDAVLLVNISTVYPDKYFDQSCILKKGCHPFVLRDSWVVYREAGPFNLARLEQGVAQKSIKTHQPINAG
DFTRIRAGFDISPDVKIKVERFMRQHKI

Nucleotide

• Length: 327 bp

>T283571 NZ_CP127126:278723-279049 [Pseudomonas aeruginosa PA14]
ATGAATGACCCCGTGTACTGCCCGGTTCTTGGGTATGACGCGGTGTTGCTTGTCAACATCTCGACTGTCTATCCAGATAA
GTATTTCGATCAGTCATGCATTCTAAAGAAGGGTTGTCATCCCTTTGTTCTGCGCGACAGCTGGGTCGTATACCGCGAGG
CAGGCCCTTTCAACCTTGCACGGCTTGAGCAAGGGGTAGCGCAGAAGTCCATCAAGACGCATCAGCCCATCAACGCAGGC
GATTTCACTCGGATTCGGGCAGGCTTCGACATCTCGCCCGACGTCAAAATCAAAGTTGAGCGGTTCATGAGGCAGCACAA
GATTTAG

Antitoxin

Protein

• Length: 186 a.a.
• Molecular weight: 21377.14 Da
• Isoelectric Point: 5.8950

>AT283571 WP_023107584.1 NZ_CP127126:278094-278651 [Pseudomonas aeruginosa PA14]
VIFSEQKVAHMAAFFLASAEGPLPHLTLIKLLYLADRESMARFDVPMSDDRAVSMPHGPVLSSTLDLIKGRLRSEVWSAW
ISPLVDHEVRLVHDVENWDDLDELSRSDRSILESVWQEFGHMTKYQLRDYTHHHIGEWHDPHGSSRDIDPKDTFMALGQS
EELAEIKARDLAERRRHGRKLSEFI

Nucleotide

• Length: 558 bp

>AT283571 NZ_CP127126:278094-278651 [Pseudomonas aeruginosa PA14]
GTGATCTTCAGTGAACAGAAAGTGGCTCACATGGCAGCTTTCTTTTTGGCGAGTGCCGAAGGGCCGCTGCCTCATCTCAC
GCTGATCAAACTGCTGTACCTGGCAGACCGAGAGTCGATGGCTCGTTTCGACGTTCCCATGTCGGACGATCGAGCTGTTT
CCATGCCCCATGGGCCTGTCCTTTCCTCGACGCTAGACCTCATCAAGGGGCGTTTGCGCTCTGAGGTTTGGAGCGCTTGG
ATTTCTCCGTTGGTGGATCACGAGGTCCGTCTGGTCCATGACGTGGAGAATTGGGACGATCTGGATGAGTTGAGCCGATC
GGATCGCAGCATTTTGGAATCGGTCTGGCAAGAGTTTGGCCACATGACCAAGTACCAATTGCGGGACTACACCCACCATC
ACATTGGTGAGTGGCACGACCCCCACGGCTCTTCCAGGGACATTGATCCAAAGGATACTTTCATGGCGCTTGGTCAAAGC
GAGGAGCTGGCGGAGATCAAGGCGCGCGATCTTGCTGAGCGCCGTCGGCACGGTAGGAAGCTGTCTGAGTTCATTTGA