Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-Phd
Location 1626038..1626600 Replicon chromosome
Accession NZ_CP127115
Organism Paenarthrobacter sp. R1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag QN084_RS07910 Protein ID WP_021472908.1
Coordinates 1626310..1626600 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A7M2BYL4
Locus tag QN084_RS07905 Protein ID WP_021472907.1
Coordinates 1626038..1626313 (+) Length 92 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QN084_RS07885 (QN084_07885) 1622261..1623298 - 1038 WP_031216691.1 zinc-dependent alcohol dehydrogenase family protein -
QN084_RS07890 (QN084_07890) 1623428..1624240 - 813 WP_021472904.1 hypothetical protein -
QN084_RS07895 (QN084_07895) 1624287..1624928 - 642 WP_021472905.1 LysE family translocator -
QN084_RS07900 (QN084_07900) 1625127..1626005 + 879 WP_043427191.1 prephenate dehydratase -
QN084_RS07905 (QN084_07905) 1626038..1626313 + 276 WP_021472907.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
QN084_RS07910 (QN084_07910) 1626310..1626600 + 291 WP_021472908.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QN084_RS07915 (QN084_07915) 1626612..1627589 - 978 WP_021472909.1 thioredoxin-disulfide reductase -
QN084_RS07920 (QN084_07920) 1627653..1629824 - 2172 WP_069696782.1 MMPL family transporter -
QN084_RS07925 (QN084_07925) 1629987..1630622 + 636 WP_259362707.1 MarR family transcriptional regulator -
QN084_RS07930 (QN084_07930) 1630703..1631518 + 816 WP_021474094.1 class I SAM-dependent methyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(14-93)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-71)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10888.46 Da        Isoelectric Point: 10.0347

>T283569 WP_021472908.1 NZ_CP127115:1626310-1626600 [Paenarthrobacter sp. R1]
VSNSSLEGEPWNIQVTSPALKTFHRLPEKAASAIVEFITGALAGNPHRLSKPLTNELLGMRTARRGDYRVLFTLDIEDHV
LYVHRIQHRADVYKPR

Download         Length: 291 bp

Antitoxin


Download         Length: 92 a.a.        Molecular weight: 10112.30 Da        Isoelectric Point: 4.6847

>AT283569 WP_021472907.1 NZ_CP127115:1626038-1626313 [Paenarthrobacter sp. R1]
MKTVPLSEAKDKLSALVEEADTTHEIIQITRHGHPSAVLMSADDLESLQETIHWLSQPGLREDLAQARRDIAEGNTVSGD
DLRREFGLPPR

Download         Length: 276 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A7M2BYL4

References