Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /RES-TIGR02293
Location 3503351..3504234 Replicon chromosome
Accession NZ_CP127114
Organism Pseudomonas sp. M2(2023)

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag QN085_RS16175 Protein ID WP_013973162.1
Coordinates 3503351..3503737 (-) Length 129 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID F8G488
Locus tag QN085_RS16180 Protein ID WP_013973163.1
Coordinates 3503785..3504234 (-) Length 150 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QN085_RS16160 (QN085_16155) 3499721..3500950 - 1230 WP_013973159.1 acyl-CoA dehydrogenase -
QN085_RS16165 (QN085_16160) 3501091..3502017 + 927 WP_013973160.1 LysR family transcriptional regulator -
QN085_RS16170 (QN085_16165) 3502189..3503343 + 1155 WP_285687309.1 aminotransferase class V-fold PLP-dependent enzyme -
QN085_RS16175 (QN085_16170) 3503351..3503737 - 387 WP_013973162.1 RES family NAD+ phosphorylase Toxin
QN085_RS16180 (QN085_16175) 3503785..3504234 - 450 WP_013973163.1 DUF2384 domain-containing protein Antitoxin
QN085_RS16185 (QN085_16180) 3504333..3504986 - 654 WP_013973164.1 oxygen-insensitive NAD(P)H-dependent nitroreductase NfsB -
QN085_RS16190 (QN085_16185) 3505091..3506014 + 924 WP_013973165.1 LysR family transcriptional regulator -
QN085_RS16195 (QN085_16190) 3506062..3506892 + 831 WP_013973166.1 AraC family transcriptional regulator -
QN085_RS16200 (QN085_16195) 3506943..3507527 + 585 WP_041505856.1 LysE family translocator -
QN085_RS16205 (QN085_16200) 3507648..3508865 - 1218 WP_041505855.1 sugar transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(3-120)

Antitoxin

Antitoxin Xre-like, helix-turn-helix domain

(33-91)


Sequences

Toxin        


Download         Length: 129 a.a.        Molecular weight: 14226.21 Da        Isoelectric Point: 5.0980

>T283568 WP_013973162.1 NZ_CP127114:c3503737-3503351 [Pseudomonas sp. M2(2023)]
MRVSGRWHQAGRPVVYAATSPAGAMLEVLVHLEIDPEDFPTTMRLLRIELPDTVSQAQLPALQPGWSSQTELTRGLGNRF
LDECSALLLPVPSAIMPSTTNYLFNPRHPQANSARLEVEDFTPDSRLF

Download         Length: 387 bp

Antitoxin


Download         Length: 150 a.a.        Molecular weight: 17004.59 Da        Isoelectric Point: 6.3405

>AT283568 WP_013973163.1 NZ_CP127114:c3504234-3503785 [Pseudomonas sp. M2(2023)]
MLAEVLRDNGYHEYRARLHALLEIPELASDFEIHTRITHGFAATWLVKLTELGVFTPVERDQIIPLRTLKTRIERDQPLT
VEESDRLFRSAHITAMAEAVFGEAGKAKRWLSKPKERFSGLTPMQMLTTQQGTTQVEEMLLQIAEGFGL

Download         Length: 450 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB F8G488

References