283566

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tsbAT/-
Location 989490..990271 Replicon chromosome
Accession NZ_CP127101
Organism Staphylococcus pseudintermedius strain 10916-77753

Toxin (Protein)


Gene name tsbT Uniprot ID -
Locus tag QQZ06_RS04625 Protein ID WP_180291797.1
Coordinates 990110..990271 (+) Length 54 a.a.

Antitoxin (Protein)


Gene name tsbA Uniprot ID A0A2A4EFJ1
Locus tag QQZ06_RS04620 Protein ID WP_014613531.1
Coordinates 989490..990089 (+) Length 200 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QQZ06_RS04600 (QQZ06_04600) 985362..986822 + 1461 WP_096636872.1 ABC transporter substrate-binding protein/permease -
QQZ06_RS04605 (QQZ06_04605) 986815..987540 + 726 WP_015729369.1 amino acid ABC transporter ATP-binding protein -
QQZ06_RS04610 (QQZ06_04610) 987696..988826 + 1131 WP_065520439.1 tRNA epoxyqueuosine(34) reductase QueG -
QQZ06_RS04615 (QQZ06_04615) 988826..989296 + 471 WP_014613530.1 tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL -
QQZ06_RS04620 (QQZ06_04620) 989490..990089 + 600 WP_014613531.1 glucosamine-6-phosphate isomerase Antitoxin
QQZ06_RS04625 (QQZ06_04625) 990110..990271 + 162 WP_180291797.1 SAS053 family protein Toxin
QQZ06_RS04630 (QQZ06_04630) 990392..990835 + 444 WP_014613533.1 hypothetical protein -
QQZ06_RS04635 (QQZ06_04635) 991065..992450 + 1386 WP_110159441.1 class II fumarate hydratase -
QQZ06_RS04640 (QQZ06_04640) 992471..993997 + 1527 WP_014613535.1 exopolyphosphatase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Glucosamine-6-phosphate isomerase

(132-197)


Sequences

Toxin        


Download         Length: 54 a.a.        Molecular weight: 6228.71 Da        Isoelectric Point: 4.2450

>T283566 WP_180291797.1 NZ_CP127101:990110-990271 [Staphylococcus pseudintermedius]
MKDEQKHYDNEMVDSFDDVVELGKEMEQISEANDEEKLNQAHDSKVRSDKNTK

Download         Length: 162 bp

Antitoxin


Download         Length: 200 a.a.        Molecular weight: 22195.27 Da        Isoelectric Point: 6.2965

>AT283566 WP_014613531.1 NZ_CP127101:989490-990089 [Staphylococcus pseudintermedius]
MAMNFKVFKDAETAATFTADILRKQLNNNPTSIVGLHLNQEEAPVLDALKKDVDRHSVDFSQIHVLDYDAQQSYYQALGV
PEKQIHHVPEDEKVESFIKHHAKTKDNKGKLTLQVVTIDTKGQIGIPMNDALLPAREIIVVVTGAVKAEQVKKLYEENGN
TTFIPSALKSHRMVTVVLDEAAAQGLPEDVRNYFTSLYA

Download         Length: 600 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A2A4EFJ1

References