283557

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tsbAT/-
Location 1053626..1054397 Replicon chromosome
Accession NZ_CP127096
Organism Staphylococcus haemolyticus strain M1691_10

Toxin (Protein)


Gene name tsbT Uniprot ID -
Locus tag QQO14_RS05360 Protein ID WP_107637350.1
Coordinates 1054248..1054397 (+) Length 50 a.a.

Antitoxin (Protein)


Gene name tsbA Uniprot ID Q4L7F8
Locus tag QQO14_RS05355 Protein ID WP_011275409.1
Coordinates 1053626..1054225 (+) Length 200 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QQO14_RS05335 1049512..1050963 + 1452 Protein_1015 ABC transporter substrate-binding protein/permease -
QQO14_RS05340 1050956..1051678 + 723 WP_016931345.1 amino acid ABC transporter ATP-binding protein -
QQO14_RS05345 1051856..1052983 + 1128 WP_240575976.1 tRNA epoxyqueuosine(34) reductase QueG -
QQO14_RS05350 1052984..1053454 + 471 WP_037538647.1 tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL -
QQO14_RS05355 1053626..1054225 + 600 WP_011275409.1 glucosamine-6-phosphate isomerase Antitoxin
QQO14_RS05360 1054248..1054397 + 150 WP_107637350.1 SAS053 family protein Toxin
QQO14_RS05365 1054608..1055003 + 396 WP_053041937.1 hypothetical protein -
QQO14_RS05370 1055211..1056596 + 1386 WP_011275412.1 class II fumarate hydratase -
QQO14_RS05375 1056659..1057483 - 825 WP_053016825.1 RluA family pseudouridine synthase -
QQO14_RS05380 1057671..1058780 + 1110 WP_285491533.1 GAF domain-containing sensor histidine kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Glucosamine-6-phosphate isomerase

(130-195)


Sequences

Toxin        


Download         Length: 50 a.a.        Molecular weight: 5782.16 Da        Isoelectric Point: 3.9365

>T283557 WP_107637350.1 NZ_CP127096:1054248-1054397 [Staphylococcus haemolyticus]
MTKNKDSELNYHEEENAMVQDLDDLKTLGKEMEQISEENDEDKLNQSHD

Download         Length: 150 bp

Antitoxin


Download         Length: 200 a.a.        Molecular weight: 22272.12 Da        Isoelectric Point: 4.7588

>AT283557 WP_011275409.1 NZ_CP127096:1053626-1054225 [Staphylococcus haemolyticus]
MAMNFKVFNDVEHVAEYTADIIRKQFNNNPTTIAGIHLTKDAAPVLDELKKDVDHNAVDFSQVNILDYDDNRSYYEALGV
PASQIYPINLDDDAESLIDDKIKTKENKGKLILQVTSIDESGSLNVNVRQGLLKAREVVLVVTGANKREVVKKLYEENGK
SSFEPSDLKAHRMVTVVLDRAAAEGLPEDVKEYFTARFA

Download         Length: 600 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A2A1K9C2

References