Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) spoIISABC/SpoIISA-SpoIISB
Location 3525116..3526032 Replicon chromosome
Accession NZ_CP127095
Organism Bacillus inaquosorum strain LBA001

Toxin (Protein)


Gene name spoIISA Uniprot ID -
Locus tag QMC72_RS17585 Protein ID WP_133487760.1
Coordinates 3525116..3525862 (+) Length 249 a.a.

Antitoxin (Protein)


Gene name spoIISB Uniprot ID G4NV07
Locus tag QMC72_RS17590 Protein ID WP_003239095.1
Coordinates 3525862..3526032 (+) Length 57 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QMC72_RS17560 (QMC72_17560) 3520200..3520346 - 147 WP_019258173.1 hypothetical protein -
QMC72_RS17565 (QMC72_17565) 3520447..3521397 - 951 WP_019258172.1 ring-cleaving dioxygenase -
QMC72_RS17570 (QMC72_17570) 3521783..3523099 + 1317 WP_088111058.1 serine/threonine exchanger -
QMC72_RS17575 (QMC72_17575) 3523375..3523992 + 618 WP_003218470.1 DUF47 domain-containing protein -
QMC72_RS17580 (QMC72_17580) 3524005..3525006 + 1002 WP_003239093.1 inorganic phosphate transporter -
QMC72_RS17585 (QMC72_17585) 3525116..3525862 + 747 WP_133487760.1 toxin-antitoxin-antitoxin system toxin SpoIISA Toxin
QMC72_RS17590 (QMC72_17590) 3525862..3526032 + 171 WP_003239095.1 three component toxin-antitoxin-antitoxin system antitoxin SpoIISB Antitoxin
QMC72_RS17595 (QMC72_17595) 3526117..3526254 + 138 WP_119913750.1 three component toxin-antitoxin-antitoxin system antitoxin SpoIISC -
QMC72_RS17600 (QMC72_17600) 3526291..3527184 - 894 WP_003239098.1 N-acetylmuramoyl-L-alanine amidase -
QMC72_RS17605 (QMC72_17605) 3527197..3527460 - 264 WP_003239099.1 phage holin -
QMC72_RS17610 (QMC72_17610) 3527473..3527742 - 270 WP_060398448.1 hemolysin XhlA family protein -
QMC72_RS17615 (QMC72_17615) 3527795..3528634 - 840 WP_133487762.1 phage portal protein -
QMC72_RS17620 (QMC72_17620) 3528681..3528845 - 165 WP_133487764.1 XkdX family protein -
QMC72_RS17625 (QMC72_17625) 3528842..3529168 - 327 WP_133487766.1 XkdW family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin SpoIISA, type II toxin-antitoxin system

(3-238)

Antitoxin

Antitoxin SpoIISB

(1-56)


Sequences

Toxin        


Download         Length: 249 a.a.        Molecular weight: 29070.54 Da        Isoelectric Point: 4.6135

>T283554 WP_133487760.1 NZ_CP127095:3525116-3525862 [Bacillus inaquosorum]
MLLFFQIMVWCVMAGLGLYVYATWRFEAKVKEKMSAIRKTWYLLFVLGAMVYWTYDPSSLFTHWERYLIVAVSFALIDAF
IFLSAYVKKLAGSELETDTREILEENNEMLHMYLNRLKTYQYLLKNEPIHVYYGSIDAYAEGIDKLLKTYADKMNLTASL
CHYSTQADKDRLTEHMDDPADVQTRLDRKDVYYDQYGKMVLIPFTIETQSYVIKLTSDSIVTEFDYLLFTSLTSIYDLVL
PIEEEGEG

Download         Length: 747 bp

Antitoxin


Download         Length: 57 a.a.        Molecular weight: 6555.59 Da        Isoelectric Point: 10.8401

>AT283554 WP_003239095.1 NZ_CP127095:3525862-3526032 [Bacillus inaquosorum]
MERAFQNGCEPRAAKPFKILKKRSTTSVASYQVSPHTARIFKENERLIDEYKRKKA

Download         Length: 171 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB G4NV07

References