283549

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PfiT-PfiA/ParE-Phd
Location 22922..23533 Replicon plasmid pPlaYM7902D
Accession NZ_CP127049
Organism Pseudomonas amygdali pv. lachrymans strain YM7902

Toxin (Protein)


Gene name PfiT Uniprot ID A0A3M3DN15
Locus tag QO021_RS31485 Protein ID WP_005746121.1
Coordinates 23183..23533 (+) Length 117 a.a.

Antitoxin (Protein)


Gene name PfiA Uniprot ID A0A3M5ISD9
Locus tag QO021_RS31480 Protein ID WP_005746122.1
Coordinates 22922..23170 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QO021_RS31450 (QO021_31445) 18873..19106 - 234 WP_005746115.1 hypothetical protein -
QO021_RS31455 (QO021_31450) 19145..19570 + 426 Protein_26 IS5/IS1182 family transposase -
QO021_RS31460 (QO021_31455) 19926..20546 - 621 WP_004642393.1 hypothetical protein -
QO021_RS31465 (QO021_31460) 20543..20809 - 267 WP_004642394.1 hypothetical protein -
QO021_RS31470 (QO021_31465) 21263..21529 + 267 WP_227024934.1 hypothetical protein -
QO021_RS31475 (QO021_31470) 21597..22574 + 978 WP_007247761.1 IS5 family transposase -
QO021_RS31480 (QO021_31475) 22922..23170 + 249 WP_005746122.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
QO021_RS31485 (QO021_31480) 23183..23533 + 351 WP_005746121.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QO021_RS31490 (QO021_31485) 23702..24160 - 459 WP_272939231.1 type III effector -
QO021_RS31495 (QO021_31490) 24396..25373 + 978 WP_007247761.1 IS5 family transposase -
QO021_RS31500 (QO021_31495) 25987..26964 + 978 WP_285230714.1 IS5 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..47967 47967
- inside IScluster/Tn - - 7350..47698 40348


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-101)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 12844.78 Da        Isoelectric Point: 4.5514

>T283549 WP_005746121.1 NZ_CP127049:23183-23533 [Pseudomonas amygdali pv. lachrymans]
MTTFALRFTEVAQQSLEDQVEHLAVTQGFSSAARRIDSLIDAIQDKLLSTPLGYPVSPQLSELGVLHYRELNTDGYRIFY
EVMDSGGITGIVVLLVLGGKQSVEQALIRYCLLQLI

Download         Length: 351 bp

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9405.72 Da        Isoelectric Point: 9.5019

>AT283549 WP_005746122.1 NZ_CP127049:22922-23170 [Pseudomonas amygdali pv. lachrymans]
MRVETISYLKRNAADLPLDEPLVVTQNGVPAYVVESYADRKRRDESIALVKLLAISSREYSQGKHCSTDELKARLSRRFD
HK

Download         Length: 249 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3M3DN15

Antitoxin

Source ID Structure
AlphaFold DB A0A3M5ISD9

References