Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RHH
Location 4054242..4054755 Replicon chromosome
Accession NZ_CP127045
Organism Pseudomonas amygdali pv. lachrymans strain YM7902

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag QO021_RS18865 Protein ID WP_004658391.1
Coordinates 4054471..4054755 (+) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A0N8T2X1
Locus tag QO021_RS18860 Protein ID WP_029241049.1
Coordinates 4054242..4054481 (+) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QO021_RS18840 (QO021_18835) 4050351..4051136 + 786 WP_002552796.1 outer membrane protein OmpK -
QO021_RS18845 (QO021_18840) 4051315..4052223 - 909 WP_005744311.1 DUF808 domain-containing protein -
QO021_RS18850 (QO021_18845) 4052373..4052879 - 507 WP_004658394.1 Lrp/AsnC family transcriptional regulator -
QO021_RS18855 (QO021_18850) 4053066..4054082 + 1017 WP_002552793.1 1-aminocyclopropane-1-carboxylate deaminase -
QO021_RS18860 (QO021_18855) 4054242..4054481 + 240 WP_029241049.1 CopG family ribbon-helix-helix protein Antitoxin
QO021_RS18865 (QO021_18860) 4054471..4054755 + 285 WP_004658391.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QO021_RS18870 (QO021_18865) 4054792..4055646 - 855 WP_004658390.1 LysR family transcriptional regulator -
QO021_RS18875 (QO021_18870) 4055721..4056653 + 933 WP_039847441.1 DMT family transporter -
QO021_RS18880 (QO021_18875) 4056684..4058612 - 1929 WP_010198401.1 methyl-accepting chemotaxis protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-89)

Antitoxin

Ribbon-helix-helix protein, CopG

(5-41)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 10647.31 Da        Isoelectric Point: 10.4249

>T283547 WP_004658391.1 NZ_CP127045:4054471-4054755 [Pseudomonas amygdali pv. lachrymans]
MQVEWLKTALKNLDEEAAYIAQDNPAAAAAFVKAIQSSVTQLASFPAMGREGRIAGTREWPLPDLPYLIPYRIRSGRLQV
LRIFHTRRQSPPVW

Download         Length: 285 bp

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8715.80 Da        Isoelectric Point: 4.4354

>AT283547 WP_029241049.1 NZ_CP127045:4054242-4054481 [Pseudomonas amygdali pv. lachrymans]
MSTMSLRLPDEMADTLAHLAKATGRSKSFLALDALREYLTREAWQIAEIQRAIEEADAGEFANTEDVKAVMDKWSGNAG

Download         Length: 240 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A0N8T2X1

References