Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/upstrm_HI1419-dnstrm_HI1420
Location 624021..624616 Replicon chromosome
Accession NZ_CP127045
Organism Pseudomonas amygdali pv. lachrymans strain YM7902

Toxin (Protein)


Gene name relE Uniprot ID A0A3M3ZKH5
Locus tag QO021_RS02965 Protein ID WP_005746690.1
Coordinates 624314..624616 (-) Length 101 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A0P9S822
Locus tag QO021_RS02960 Protein ID WP_005746689.1
Coordinates 624021..624311 (-) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QO021_RS02945 (QO021_02945) 621583..622956 - 1374 WP_005746685.1 PepSY domain-containing protein -
QO021_RS02950 (QO021_02950) 623041..623475 - 435 WP_005746686.1 DUF2946 domain-containing protein -
QO021_RS02955 (QO021_02955) 623489..623950 - 462 WP_005746687.1 copper chaperone PCu(A)C -
QO021_RS02960 (QO021_02960) 624021..624311 - 291 WP_005746689.1 putative addiction module antidote protein Antitoxin
QO021_RS02965 (QO021_02965) 624314..624616 - 303 WP_005746690.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QO021_RS02970 (QO021_02970) 624766..625506 - 741 WP_005746691.1 cobalt-precorrin-6A reductase -
QO021_RS02975 (QO021_02975) 625503..626615 - 1113 WP_005746694.1 cobalt-precorrin-5B (C(1))-methyltransferase -
QO021_RS02980 (QO021_02980) 626615..627817 - 1203 WP_005746695.1 bifunctional cobalt-precorrin-7 (C(5))-methyltransferase/cobalt-precorrin-6B (C(15))-methyltransferase -
QO021_RS02985 (QO021_02985) 627943..629283 + 1341 WP_080164792.1 precorrin-3B synthase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(12-86)

Antitoxin

Uncharacterized protein HI1420

(4-95)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11477.21 Da        Isoelectric Point: 10.6008

>T283546 WP_005746690.1 NZ_CP127045:c624616-624314 [Pseudomonas amygdali pv. lachrymans]
MNRFEQTPAFAEWLRSLKDSIGRARILARIRAAELGNFGDCDALGQGVRELRIHHGPGYRVYFARRTGVVYLLLIAGDKS
SQKRDIKFARQLARELCERE

Download         Length: 303 bp

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10500.87 Da        Isoelectric Point: 4.5720

>AT283546 WP_005746689.1 NZ_CP127045:c624311-624021 [Pseudomonas amygdali pv. lachrymans]
MNNETTPFDTVDYLKTPEDMANYLDACLEEDSGDGLLVRAALNDIARAYGMTQIARDTGLGRESLYKALGANGNPEFTTI
MKVVRAMGIKLHASTR

Download         Length: 291 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3M3ZKH5

Antitoxin

Source ID Structure
AlphaFold DB A0A0P9S822

References