Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) PumAB/COG3657-dnstrm_HI1420
Location 4080793..4081396 Replicon chromosome
Accession NZ_CP126994
Organism Acidisoma sp. PAMC 29798

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag QP803_RS19630 Protein ID WP_284947970.1
Coordinates 4081091..4081396 (-) Length 102 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag QP803_RS19625 Protein ID WP_284945151.1
Coordinates 4080793..4081098 (-) Length 102 a.a.

Genomic Context


QP803_RS19610QP803_RS19615QP803_RS19635QP803_RS19645QP803_RS19660QP803_RS19595QP803_RS19600QP803_RS19605QP803_RS19620QP803_RS19625QP803_RS19630QP803_RS19640QP803_RS19650QP803_RS19655
Location: 4077880..4078968 (1089 bp)
Type: Others
Protein ID: WP_284945148.1
Location: 4079314..4080021 (708 bp)
Type: Others
Protein ID: WP_284945149.1
Location: 4081844..4082329 (486 bp)
Type: Others
Protein ID: WP_284945152.1
Location: 4083270..4083905 (636 bp)
Type: Others
Protein ID: Protein_3883
Location: 4085566..4085991 (426 bp)
Type: Others
Protein ID: WP_284945156.1
Location: 4075806..4076120 (315 bp)
Type: Others
Protein ID: WP_284945145.1
Location: 4076514..4077680 (1167 bp)
Type: Others
Protein ID: WP_284945146.1
Location: 4077702..4077881 (180 bp)
Type: Others
Protein ID: WP_284945147.1
Location: 4080080..4080724 (645 bp)
Type: Others
Protein ID: WP_284945150.1
Location: 4080793..4081098 (306 bp)
Type: Antitoxin
Protein ID: WP_284945151.1
Location: 4081091..4081396 (306 bp)
Type: Toxin
Protein ID: WP_284947970.1
Location: 4082355..4083146 (792 bp)
Type: Others
Protein ID: WP_284945153.1
Location: 4084567..4084773 (207 bp)
Type: Others
Protein ID: WP_284945154.1
Location: 4084845..4085417 (573 bp)
Type: Others
Protein ID: WP_284945155.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
QP803_RS195954075806..4076120-315WP_284945145.1WGR domain-containing protein-
QP803_RS196004076514..4077680-1167WP_284945146.1ISKra4 family transposase-
QP803_RS196054077702..4077881-180WP_284945147.1hypothetical protein-
QP803_RS196104077880..4078968+1089WP_284945148.1IS66 family transposase-
QP803_RS196154079314..4080021+708WP_284945149.1IS6 family transposase-
QP803_RS196204080080..4080724-645WP_284945150.1hypothetical protein-
QP803_RS196254080793..4081098-306WP_284945151.1putative addiction module antidote proteinAntitoxin
QP803_RS196304081091..4081396-306WP_284947970.1type II toxin-antitoxin system RelE/ParE family toxinToxin
QP803_RS196354081844..4082329+486WP_284945152.1IS6 family transposase-
QP803_RS196404082355..4083146-792WP_284945153.1IS6 family transposase-
QP803_RS196454083270..4083905+636Protein_3883IS5 family transposase-
QP803_RS196504084567..4084773-207WP_284945154.1hypothetical protein-
QP803_RS196554084845..4085417-573WP_284945155.1hypothetical protein-
QP803_RS196604085566..4085991+426WP_284945156.1hypothetical protein-

Associated MGEs


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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideProphage--4072743..408390511162
-flankIS/Tn--4083225..4083905680


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.



Sequences


Toxin        


Download         Length: 102 a.a.        Molecular weight: 11267.97 Da        Isoelectric Point: 9.8903

>T283483 WP_284947970.1 NZ_CP126994:c4081396-4081091 [Acidisoma sp. PAMC 29798]
VIELKQTETFIKWEGRLRDKRAKTMIAARLARLAHGLPGDVESVGEGVSELRIHYGPGYRVYFQQRGAVLIVLLCGGDKK
TQARDIVTAKKLANEWSDTDG

Download         Length: 306 bp


Antitoxin


Download         Length: 102 a.a.        Molecular weight: 10652.98 Da        Isoelectric Point: 4.5388

>AT283483 WP_284945151.1 NZ_CP126994:c4081098-4080793 [Acidisoma sp. PAMC 29798]
MAEKLTTYDPAAALVDDEEIAAFMADAFESGDAGYIANALGIVARAKGMTQIASQTGLSREQLYRSFSEAGNPTLKTTLS
VMKALGIDLTAKPHNRQDASA

Download         Length: 306 bp


Similar Proteins


Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures


Toxin

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Source
ID
Structure
No matching records found


Antitoxin

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Source
ID
Structure
No matching records found

References