Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/COG3657-dnstrm_HI1420
Location 4080793..4081396 Replicon chromosome
Accession NZ_CP126994
Organism Acidisoma sp. PAMC 29798

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag QP803_RS19630 Protein ID WP_284947970.1
Coordinates 4081091..4081396 (-) Length 102 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag QP803_RS19625 Protein ID WP_284945151.1
Coordinates 4080793..4081098 (-) Length 102 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QP803_RS19595 4075806..4076120 - 315 WP_284945145.1 WGR domain-containing protein -
QP803_RS19600 4076514..4077680 - 1167 WP_284945146.1 ISKra4 family transposase -
QP803_RS19605 4077702..4077881 - 180 WP_284945147.1 hypothetical protein -
QP803_RS19610 4077880..4078968 + 1089 WP_284945148.1 IS66 family transposase -
QP803_RS19615 4079314..4080021 + 708 WP_284945149.1 IS6 family transposase -
QP803_RS19620 4080080..4080724 - 645 WP_284945150.1 hypothetical protein -
QP803_RS19625 4080793..4081098 - 306 WP_284945151.1 putative addiction module antidote protein Antitoxin
QP803_RS19630 4081091..4081396 - 306 WP_284947970.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QP803_RS19635 4081844..4082329 + 486 WP_284945152.1 IS6 family transposase -
QP803_RS19640 4082355..4083146 - 792 WP_284945153.1 IS6 family transposase -
QP803_RS19645 4083270..4083905 + 636 Protein_3883 IS5 family transposase -
QP803_RS19650 4084567..4084773 - 207 WP_284945154.1 hypothetical protein -
QP803_RS19655 4084845..4085417 - 573 WP_284945155.1 hypothetical protein -
QP803_RS19660 4085566..4085991 + 426 WP_284945156.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 4072743..4083905 11162
- flank IS/Tn - - 4083225..4083905 680


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(3-96)

Antitoxin

Uncharacterized protein HI1420

(4-97)


Sequences

Toxin        


Download         Length: 102 a.a.        Molecular weight: 11267.97 Da        Isoelectric Point: 9.8903

>T283483 WP_284947970.1 NZ_CP126994:c4081396-4081091 [Acidisoma sp. PAMC 29798]
VIELKQTETFIKWEGRLRDKRAKTMIAARLARLAHGLPGDVESVGEGVSELRIHYGPGYRVYFQQRGAVLIVLLCGGDKK
TQARDIVTAKKLANEWSDTDG

Download         Length: 306 bp

Antitoxin


Download         Length: 102 a.a.        Molecular weight: 10652.98 Da        Isoelectric Point: 4.5388

>AT283483 WP_284945151.1 NZ_CP126994:c4081098-4080793 [Acidisoma sp. PAMC 29798]
MAEKLTTYDPAAALVDDEEIAAFMADAFESGDAGYIANALGIVARAKGMTQIASQTGLSREQLYRSFSEAGNPTLKTTLS
VMKALGIDLTAKPHNRQDASA

Download         Length: 306 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References