Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) shpAB/BrnT-BrnA
Location 2683865..2684486 Replicon chromosome
Accession NZ_CP126994
Organism Acidisoma sp. PAMC 29798

Toxin (Protein)


Gene name shpA Uniprot ID -
Locus tag QP803_RS12975 Protein ID WP_284943892.1
Coordinates 2684157..2684486 (-) Length 110 a.a.

Antitoxin (Protein)


Gene name shpB Uniprot ID -
Locus tag QP803_RS12970 Protein ID WP_284943891.1
Coordinates 2683865..2684176 (-) Length 104 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QP803_RS12960 2679235..2681337 - 2103 WP_284943890.1 protein-disulfide reductase DsbD family protein -
QP803_RS12965 2681419..2683857 + 2439 WP_284947908.1 ATP-dependent helicase HrpB -
QP803_RS12970 2683865..2684176 - 312 WP_284943891.1 BrnA antitoxin family protein Antitoxin
QP803_RS12975 2684157..2684486 - 330 WP_284943892.1 BrnT family toxin Toxin
QP803_RS12980 2684584..2685687 + 1104 WP_284943893.1 NAD-binding protein -
QP803_RS12985 2685745..2686521 - 777 WP_284943894.1 gamma-glutamyl-gamma-aminobutyrate hydrolase family protein -
QP803_RS12990 2686715..2687770 + 1056 WP_284943895.1 dTDP-glucose 4,6-dehydratase -
QP803_RS12995 2687814..2688698 + 885 WP_284943896.1 glucose-1-phosphate thymidylyltransferase RfbA -
QP803_RS13000 2688711..2689271 + 561 WP_284943897.1 dTDP-4-dehydrorhamnose 3,5-epimerase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(19-100)

Antitoxin

BrnA antitoxin of type II toxin-antitoxin system

(41-96)


Sequences

Toxin        


Download         Length: 110 a.a.        Molecular weight: 12713.66 Da        Isoelectric Point: 8.6044

>T283482 WP_284943892.1 NZ_CP126994:c2684486-2684157 [Acidisoma sp. PAMC 29798]
MDWFYKFVVTRAVNVRVEWDPVKADQNLRKHRVSFALAMRVFFDPLALVEQDRVEGGEERWQTLGMVDGVTLLLVAHTML
DGGAIEVIRIISARRAEPKERRNYEQAQR

Download         Length: 330 bp

Antitoxin


Download         Length: 104 a.a.        Molecular weight: 11568.16 Da        Isoelectric Point: 7.2027

>AT283482 WP_284943891.1 NZ_CP126994:c2684176-2683865 [Acidisoma sp. PAMC 29798]
MSKHSVRRLVDLSSPPPLTDDERAELAILSSMPDDEIDTSDIPPLTDAFWKAAVQNPFYKPTKTSTTVRIDSDVLAWLRG
HGKGYQSRINAILRREMLTSLKS

Download         Length: 312 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References