Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/PemK-MazE
Location 2600015..2600562 Replicon chromosome
Accession NZ_CP126994
Organism Acidisoma sp. PAMC 29798

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag QP803_RS12610 Protein ID WP_284947902.1
Coordinates 2600236..2600562 (+) Length 109 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag QP803_RS12605 Protein ID WP_284943826.1
Coordinates 2600015..2600239 (+) Length 75 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QP803_RS12585 2595310..2596155 - 846 WP_284947901.1 undecaprenyl-diphosphate phosphatase -
QP803_RS12590 2596237..2597505 + 1269 WP_284943823.1 transcription antitermination factor NusB -
QP803_RS12595 2597651..2597848 + 198 WP_284943824.1 hypothetical protein -
QP803_RS12600 2598060..2599889 + 1830 WP_284943825.1 translational GTPase TypA -
QP803_RS12605 2600015..2600239 + 225 WP_284943826.1 antitoxin MazE family protein Antitoxin
QP803_RS12610 2600236..2600562 + 327 WP_284947902.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
QP803_RS12615 2600617..2601921 + 1305 WP_284943827.1 MFS transporter -
QP803_RS12620 2601926..2602639 + 714 WP_284943828.1 CoA transferase subunit A -
QP803_RS12625 2602651..2603301 + 651 WP_284943829.1 CoA transferase subunit B -
QP803_RS12630 2603298..2604518 - 1221 WP_284943830.1 MFS transporter -
QP803_RS12635 2604686..2605348 - 663 WP_284943831.1 glutathione S-transferase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(3-103)

Antitoxin

Antitoxin MazE-like

(8-72)


Sequences

Toxin        


Download         Length: 109 a.a.        Molecular weight: 11622.51 Da        Isoelectric Point: 8.0808

>T283481 WP_284947902.1 NZ_CP126994:2600236-2600562 [Acidisoma sp. PAMC 29798]
IVRGDLLTVAVHGDFGKHRPALVIQADQFSEHTTVTVLPLSSSMVDAPLLRITVQPSTENGLRAPSQVMIDKATTIKREK
AGSAFGRIETATLVEIERCLAVFLGIAK

Download         Length: 327 bp

Antitoxin


Download         Length: 75 a.a.        Molecular weight: 8355.46 Da        Isoelectric Point: 7.1668

>AT283481 WP_284943826.1 NZ_CP126994:2600015-2600239 [Acidisoma sp. PAMC 29798]
MATPPGNARVQKHRDALRHAGLRPVQIWVPDTRRPEFAAECRRQSVLVAEADRSDMGLRQFMDEAIADLDGWTA

Download         Length: 225 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References