Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/upstrm_HI1419-dnstrm_HI1420
Location 2554561..2555158 Replicon chromosome
Accession NZ_CP126994
Organism Acidisoma sp. PAMC 29798

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag QP803_RS12345 Protein ID WP_284943776.1
Coordinates 2554856..2555158 (-) Length 101 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag QP803_RS12340 Protein ID WP_284943775.1
Coordinates 2554561..2554866 (-) Length 102 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QP803_RS12320 2551148..2551648 - 501 WP_284943772.1 DUF2059 domain-containing protein -
QP803_RS12325 2551645..2553096 - 1452 WP_284943773.1 NAD(P)-dependent oxidoreductase -
QP803_RS12330 2553299..2554285 - 987 WP_284943774.1 complex I NDUFA9 subunit family protein -
QP803_RS12340 2554561..2554866 - 306 WP_284943775.1 putative addiction module antidote protein Antitoxin
QP803_RS12345 2554856..2555158 - 303 WP_284943776.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QP803_RS12350 2555300..2555797 - 498 WP_284943777.1 hypothetical protein -
QP803_RS12355 2555884..2556210 - 327 WP_284943778.1 HigA family addiction module antitoxin -
QP803_RS12360 2556227..2556508 - 282 WP_284943779.1 type II toxin-antitoxin system RelE/ParE family toxin -
QP803_RS12365 2556672..2557787 + 1116 WP_284943780.1 TIGR03364 family FAD-dependent oxidoreductase -
QP803_RS12370 2557784..2558590 + 807 WP_284943781.1 phosphonoacetaldehyde hydrolase -
QP803_RS12375 2558587..2559966 + 1380 WP_284943782.1 aspartate aminotransferase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-95)

Antitoxin

Uncharacterized protein HI1420

(5-90)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11179.70 Da        Isoelectric Point: 10.0379

>T283480 WP_284943776.1 NZ_CP126994:c2555158-2554856 [Acidisoma sp. PAMC 29798]
MIDVRQTSTFSDWLDGVRDRPAGQRINLRIRRVSLGNFGDVKLVGEGVSELRIDYGPGYRIYVRRRGLTVVLLLCGGDKS
TQDRDIARAKTLAKEDDNGA

Download         Length: 303 bp

>T283480 NZ_CP126994:c2555158-2554856 [Acidisoma sp. PAMC 29798]
ATGATCGACGTCCGGCAGACCTCGACCTTCTCTGACTGGCTCGATGGCGTTCGTGATCGGCCCGCGGGTCAGCGCATCAA
CCTGCGTATCCGACGCGTCTCGCTTGGCAATTTCGGTGATGTGAAACTGGTGGGAGAGGGCGTTTCGGAACTGCGGATCG
ACTACGGCCCAGGCTATCGCATCTATGTCAGGCGACGCGGCCTGACCGTTGTTCTGCTGCTGTGTGGCGGCGACAAATCG
ACGCAGGATCGCGACATCGCGCGCGCAAAGACTCTGGCAAAGGAAGACGACAATGGCGCTTGA

Antitoxin


Download         Length: 102 a.a.        Molecular weight: 11016.37 Da        Isoelectric Point: 4.4076

>AT283480 WP_284943775.1 NZ_CP126994:c2554866-2554561 [Acidisoma sp. PAMC 29798]
MALETTGWDPTDQLRSPEDEQAYIEAAFEEGDPDLIAAAIGDIARARGMAQIAREAGVSREAMYKSFRAGGNPTLDTVAR
VTRVLGLRLLVRPQPEQDACR

Download         Length: 306 bp

>AT283480 NZ_CP126994:c2554866-2554561 [Acidisoma sp. PAMC 29798]
ATGGCGCTTGAGACGACGGGATGGGACCCCACCGACCAACTCCGCTCGCCCGAGGATGAGCAGGCCTACATAGAAGCCGC
CTTCGAGGAAGGCGACCCCGACCTCATCGCGGCCGCCATCGGTGACATTGCCCGCGCACGCGGCATGGCGCAGATCGCGC
GCGAAGCCGGTGTCAGCCGAGAGGCGATGTACAAGTCGTTCCGCGCCGGCGGTAACCCTACACTCGATACGGTCGCGCGT
GTCACAAGGGTGTTAGGCCTGCGACTGCTGGTGCGCCCGCAGCCGGAGCAGGATGCGTGTAGGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References