Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) shpA-brnA/BrnT-BrnA
Location 2097615..2098161 Replicon chromosome
Accession NZ_CP126994
Organism Acidisoma sp. PAMC 29798

Toxin (Protein)


Gene name shpA Uniprot ID -
Locus tag QP803_RS10120 Protein ID WP_284947635.1
Coordinates 2097877..2098161 (-) Length 95 a.a.

Antitoxin (Protein)


Gene name brnA Uniprot ID -
Locus tag QP803_RS10115 Protein ID WP_284947634.1
Coordinates 2097615..2097890 (-) Length 92 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QP803_RS10090 2093090..2093287 + 198 WP_284947629.1 YqaE/Pmp3 family membrane protein -
QP803_RS10095 2093284..2093574 + 291 WP_284947630.1 putative quinol monooxygenase -
QP803_RS10100 2093611..2094912 - 1302 WP_284947631.1 glycolate oxidase subunit GlcF -
QP803_RS10105 2094921..2096114 - 1194 WP_284947632.1 FAD-binding protein -
QP803_RS10110 2096111..2097547 - 1437 WP_284947633.1 FAD-linked oxidase C-terminal domain-containing protein -
QP803_RS10115 2097615..2097890 - 276 WP_284947634.1 BrnA antitoxin family protein Antitoxin
QP803_RS10120 2097877..2098161 - 285 WP_284947635.1 BrnT family toxin Toxin
QP803_RS10125 2098289..2099527 + 1239 WP_284947636.1 DNA topoisomerase IB -
QP803_RS10130 2099561..2099737 - 177 WP_284947637.1 DUF3309 domain-containing protein -
QP803_RS10135 2099838..2100548 - 711 WP_284947638.1 methyltransferase domain-containing protein -
QP803_RS10140 2100639..2101370 + 732 WP_284947639.1 hydroxyacylglutathione hydrolase -
QP803_RS10145 2101409..2102005 + 597 WP_284947640.1 glutathione S-transferase N-terminal domain-containing protein -
QP803_RS10150 2102011..2102454 + 444 WP_284947641.1 cupin domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(6-85)

Antitoxin

BrnA antitoxin of type II toxin-antitoxin system

(20-83)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 10747.10 Da        Isoelectric Point: 6.4863

>T283479 WP_284947635.1 NZ_CP126994:c2098161-2097877 [Acidisoma sp. PAMC 29798]
VPRFTWNAAKARSNLLKHGVAFEDAELVWRDPRHLLRFDRIEDGEERWHAIGLAGSVVVLLVAHTDTEDGDIIRLLSARR
ATKAERKAYENDDV

Download         Length: 285 bp

Antitoxin


Download         Length: 92 a.a.        Molecular weight: 10165.44 Da        Isoelectric Point: 7.0133

>AT283479 WP_284947634.1 NZ_CP126994:c2097890-2097615 [Acidisoma sp. PAMC 29798]
MTTSRDQRDRLERLAGAPDATIDTSDIPEVLDWSGAVRGGLYKPLKEAITIRLDADVLAWFKEQVGGGRGYQSEINRVLR
QHIATIARSRD

Download         Length: 276 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References