Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 1854622..1855265 Replicon chromosome
Accession NZ_CP126994
Organism Acidisoma sp. PAMC 29798

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag QP803_RS08910 Protein ID WP_284947412.1
Coordinates 1854622..1855011 (-) Length 130 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag QP803_RS08915 Protein ID WP_284947413.1
Coordinates 1855026..1855265 (-) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QP803_RS08885 1850354..1850656 - 303 WP_284947407.1 putative addiction module antidote protein -
QP803_RS08890 1850631..1850957 - 327 WP_284947408.1 type II toxin-antitoxin system RelE/ParE family toxin -
QP803_RS08895 1851005..1852465 - 1461 WP_284947409.1 exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase -
QP803_RS08900 1852551..1853900 - 1350 WP_284947410.1 adenylosuccinate lyase -
QP803_RS08905 1853990..1854616 + 627 WP_284947411.1 YjbE family putative metal transport protein -
QP803_RS08910 1854622..1855011 - 390 WP_284947412.1 type II toxin-antitoxin system VapC family toxin Toxin
QP803_RS08915 1855026..1855265 - 240 WP_284947413.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
QP803_RS08920 1855325..1856104 - 780 WP_284947414.1 ATP-binding cassette domain-containing protein -
QP803_RS08925 1856101..1856886 - 786 WP_284947415.1 ABC transporter permease -
QP803_RS08930 1856883..1857950 - 1068 WP_284947416.1 alanine racemase -
QP803_RS08935 1857952..1859229 - 1278 WP_284947417.1 NAD(P)/FAD-dependent oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(1-111)

Antitoxin

SpoVT-AbrB domain

(10-52)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 13859.96 Da        Isoelectric Point: 6.2188

>T283478 WP_284947412.1 NZ_CP126994:c1855011-1854622 [Acidisoma sp. PAMC 29798]
MLDTNIVSDLIRNPVGRVAEQLLLHGNDGLCLSIITAAELRYGAAKKGSDRLSARVSAVLGTLDILPFDSPADAEYGKLR
AALEAAGTPIRPTDLFIAAHALALQVTLVTHNVSEFRWVRGLTVENWLA

Download         Length: 390 bp

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 9033.26 Da        Isoelectric Point: 4.3654

>AT283478 WP_284947413.1 NZ_CP126994:c1855265-1855026 [Acidisoma sp. PAMC 29798]
MSEARQVRLFRNGRNQAVRIPVEFELPGEAALMRREGNRLVIEPIRKGGLIELLATWDPIDDDFADFDEGLQPARDIDL

Download         Length: 240 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References