Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 1430763..1431424 Replicon chromosome
Accession NZ_CP126994
Organism Acidisoma sp. PAMC 29798

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag QP803_RS06870 Protein ID WP_284947042.1
Coordinates 1431020..1431424 (+) Length 135 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag QP803_RS06865 Protein ID WP_284947041.1
Coordinates 1430763..1431023 (+) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QP803_RS06850 1426263..1428770 - 2508 WP_284947038.1 FAD-dependent oxidoreductase -
QP803_RS06855 1428861..1430285 - 1425 WP_284947039.1 amidase -
QP803_RS06860 1430282..1430686 - 405 WP_284947040.1 VOC family protein -
QP803_RS06865 1430763..1431023 + 261 WP_284947041.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
QP803_RS06870 1431020..1431424 + 405 WP_284947042.1 type II toxin-antitoxin system VapC family toxin Toxin
QP803_RS06875 1431438..1432544 - 1107 WP_284947843.1 hybrid-cluster NAD(P)-dependent oxidoreductase -
QP803_RS06880 1432554..1433834 - 1281 WP_284947043.1 aromatic ring-hydroxylating dioxygenase subunit alpha -
QP803_RS06885 1433950..1435056 - 1107 WP_284947044.1 GlxA family transcriptional regulator -
QP803_RS06890 1435097..1435906 - 810 WP_284947045.1 transglutaminase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-122)

Antitoxin

SpoVT-AbrB domain

(8-55)


Sequences

Toxin        


Download         Length: 135 a.a.        Molecular weight: 14886.25 Da        Isoelectric Point: 7.1668

>T283474 WP_284947042.1 NZ_CP126994:1431020-1431424 [Acidisoma sp. PAMC 29798]
MTRYMLDTNTVSYFVKEQAEVVRRVISVPMSSLCLSAITEGELLFGLAKRPSATRLHRSVRELLRRIDVLPWTSATAERY
GVERAQMAREGRILAPIDLLIAAHALSVGAVLVTNDQVFASVTDLIVEDWTQAA

Download         Length: 405 bp

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9671.70 Da        Isoelectric Point: 4.5720

>AT283474 WP_284947041.1 NZ_CP126994:1430763-1431023 [Acidisoma sp. PAMC 29798]
MTQVAKLFSNGRSQAVRLPAAYRFEGTEVFIRQDQESGDVILSRKPPTWDGFFAALKGADVPADFLDASERHQAPQERDP
FADWSE

Download         Length: 261 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References