Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 1293424..1294055 Replicon chromosome
Accession NZ_CP126994
Organism Acidisoma sp. PAMC 29798

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag QP803_RS06220 Protein ID WP_284946918.1
Coordinates 1293663..1294055 (+) Length 131 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag QP803_RS06215 Protein ID WP_284946917.1
Coordinates 1293424..1293666 (+) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QP803_RS06200 1288617..1290323 + 1707 WP_284946914.1 GGDEF domain-containing protein -
QP803_RS06205 1290459..1291805 + 1347 WP_284946915.1 chloride channel protein -
QP803_RS06210 1291790..1293256 - 1467 WP_284946916.1 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase -
QP803_RS06215 1293424..1293666 + 243 WP_284946917.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
QP803_RS06220 1293663..1294055 + 393 WP_284946918.1 type II toxin-antitoxin system VapC family toxin Toxin
QP803_RS06225 1294052..1295446 - 1395 WP_284946919.1 MFS transporter -
QP803_RS06230 1295460..1296680 - 1221 WP_284946920.1 MFS transporter -
QP803_RS06235 1296712..1297722 - 1011 WP_284946921.1 RluA family pseudouridine synthase -
QP803_RS06240 1297762..1298049 + 288 WP_284946922.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-121)

Antitoxin

SpoVT-AbrB domain

(7-46)


Sequences

Toxin        


Download         Length: 131 a.a.        Molecular weight: 14391.54 Da        Isoelectric Point: 6.9894

>T283473 WP_284946918.1 NZ_CP126994:1293663-1294055 [Acidisoma sp. PAMC 29798]
VIYLLDSNAVIALFAGHLGFITRLKHHRPTDVGLSSIVAHELYFGAYKSRKQAENLARVEAHLFEVLPFDQQDARQAGEL
RAALSVSGTPIGPYDVLIAGQALAKGLTLITRNLREFERVPSLLVENWEV

Download         Length: 393 bp

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9198.39 Da        Isoelectric Point: 4.3193

>AT283473 WP_284946917.1 NZ_CP126994:1293424-1293666 [Acidisoma sp. PAMC 29798]
MDIAKIFWSGRSQAVRLPKEYRFDVGEVRIRRQGNALVLEPVPRDWAWLDGVTGPLDADFVEAVGEQPPEQVRPDLDFFE

Download         Length: 243 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References