Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ataT-TacA2/DUF1778(antitoxin)
Location 140700..141463 Replicon chromosome
Accession NZ_CP126994
Organism Acidisoma sp. PAMC 29798

Toxin (Protein)


Gene name ataT Uniprot ID -
Locus tag QP803_RS00710 Protein ID WP_284945770.1
Coordinates 140700..141197 (-) Length 166 a.a.

Antitoxin (Protein)


Gene name TacA2 Uniprot ID -
Locus tag QP803_RS00715 Protein ID WP_284945771.1
Coordinates 141185..141463 (-) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QP803_RS00685 135729..136844 + 1116 WP_284945766.1 bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD -
QP803_RS00690 136934..137563 + 630 WP_284947784.1 GTP cyclohydrolase II RibA -
QP803_RS00695 137653..138540 + 888 WP_284945767.1 formyltetrahydrofolate deformylase -
QP803_RS00700 138547..139422 + 876 WP_284945768.1 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD -
QP803_RS00705 139431..140636 - 1206 WP_284945769.1 MFS transporter -
QP803_RS00710 140700..141197 - 498 WP_284945770.1 GNAT family N-acetyltransferase Toxin
QP803_RS00715 141185..141463 - 279 WP_284945771.1 DUF1778 domain-containing protein Antitoxin
QP803_RS00720 141515..142753 - 1239 WP_284945772.1 arsenic transporter -
QP803_RS00725 142759..144483 - 1725 WP_284945773.1 NADPH-dependent assimilatory sulfite reductase hemoprotein subunit -
QP803_RS00730 144494..146287 - 1794 WP_284945774.1 flavodoxin domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(46-144)

Antitoxin

Vibrio phage ICP1, Orf50

(9-91)


Sequences

Toxin        


Download         Length: 166 a.a.        Molecular weight: 17824.69 Da        Isoelectric Point: 9.7355

>T283472 WP_284945770.1 NZ_CP126994:c141197-140700 [Acidisoma sp. PAMC 29798]
MGAVIQPPTRLTAAHDVSNFTCRESALNEWLLKQALRNEGRLSRSYVTCVDHQVVGFYCLVNGAVRRDAAVSKLRRNAPD
PVPVMIIGRLAVDQAWEGRGLGRGLLRDAILRTLGASEIAGIAALLVHAISPGARRFYEGSGFVASELERMTLMISLKDA
AALLG

Download         Length: 498 bp

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10209.78 Da        Isoelectric Point: 7.0134

>AT283472 WP_284945771.1 NZ_CP126994:c141463-141185 [Acidisoma sp. PAMC 29798]
MAANGPAAPTVNMRVSRSDLDLIDRAAKAHGTNRSAFMIEAAMAKAEAVLLDKRLFAVDDAIYERFMARLDEPPRIDSRL
QRLLSTPAPWEL

Download         Length: 279 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References