Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) AbkB-brnA/BrnT-BrnA
Location 42591..43197 Replicon chromosome
Accession NZ_CP126994
Organism Acidisoma sp. PAMC 29798

Toxin (Protein)


Gene name AbkB Uniprot ID -
Locus tag QP803_RS00200 Protein ID WP_284945674.1
Coordinates 42901..43197 (-) Length 99 a.a.

Antitoxin (Protein)


Gene name brnA Uniprot ID -
Locus tag QP803_RS00195 Protein ID WP_284945673.1
Coordinates 42591..42920 (-) Length 110 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QP803_RS00175 37876..39114 + 1239 WP_284945669.1 ADP-dependent glucokinase/phosphofructokinase -
QP803_RS00180 39101..40123 + 1023 WP_284945670.1 hypothetical protein -
QP803_RS00185 40151..41551 + 1401 WP_284945671.1 FAD-binding oxidoreductase -
QP803_RS00190 41553..42512 - 960 WP_284945672.1 alpha/beta hydrolase -
QP803_RS00195 42591..42920 - 330 WP_284945673.1 BrnA antitoxin family protein Antitoxin
QP803_RS00200 42901..43197 - 297 WP_284945674.1 BrnT family toxin Toxin
QP803_RS00205 43363..43824 + 462 WP_284945675.1 VOC family protein -
QP803_RS00210 43959..45146 + 1188 WP_284945676.1 MFS transporter -
QP803_RS00215 45166..45732 + 567 WP_284945677.1 cytochrome b -
QP803_RS00220 45738..47993 - 2256 WP_284945678.1 xanthine dehydrogenase family protein molybdopterin-binding subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(7-89)

Antitoxin

BrnA antitoxin of type II toxin-antitoxin system

(20-97)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11217.55 Da        Isoelectric Point: 6.4830

>T283471 WP_284945674.1 NZ_CP126994:c43197-42901 [Acidisoma sp. PAMC 29798]
MISRWTWNLRKDQTNRRDHGGLSLADGMPVLDGDPHQLSRPDTHPDGDRWQTIGMALDVLLLFVVHTEPDDRRDGIGRII
SVRRASPQERKAYEEGAF

Download         Length: 297 bp

Antitoxin


Download         Length: 110 a.a.        Molecular weight: 12290.92 Da        Isoelectric Point: 10.1530

>AT283471 WP_284945673.1 NZ_CP126994:c42920-42591 [Acidisoma sp. PAMC 29798]
MKKALSSFAKPTATSDLRKIDDDSLARLKAAATQSDQSINLSDPDAPESLDWSNATRGRFYKPVKVLKSLRIDADVLDYY
ESQGPGYQTRINRDLRLMMLQNSKRKQPA

Download         Length: 330 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References