283468

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hicAB/HicA-HicB
Location 4392211..4392833 Replicon chromosome
Accession NZ_CP126992
Organism Pseudomonas syringae pv. antirrhini str. 126

Toxin (Protein)


Gene name hicA Uniprot ID Q886E5
Locus tag QQF68_RS19815 Protein ID WP_011103638.1
Coordinates 4392651..4392833 (-) Length 61 a.a.

Antitoxin (Protein)


Gene name hicB Uniprot ID -
Locus tag QQF68_RS19810 Protein ID WP_057418502.1
Coordinates 4392211..4392615 (-) Length 135 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QQF68_RS19795 (QQF68_19795) 4387981..4388649 + 669 WP_057418504.1 ABC transporter ATP-binding protein -
QQF68_RS19800 (QQF68_19800) 4388649..4391126 + 2478 WP_011103640.1 FtsX-like permease family protein -
QQF68_RS19805 (QQF68_19805) 4391116..4392195 + 1080 WP_057418503.1 lipocalin-like domain-containing protein -
QQF68_RS19810 (QQF68_19810) 4392211..4392615 - 405 WP_057418502.1 type II toxin-antitoxin system HicB family antitoxin Antitoxin
QQF68_RS19815 (QQF68_19815) 4392651..4392833 - 183 WP_011103638.1 type II toxin-antitoxin system HicA family toxin Toxin
QQF68_RS19820 (QQF68_19820) 4393118..4394890 + 1773 WP_057418501.1 N-acetylglutaminylglutamine amidotransferase -
QQF68_RS19825 (QQF68_19825) 4394894..4396642 + 1749 WP_044392447.1 N-acetylglutaminylglutamine synthetase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HicA mRNA interferase family

(3-59)

Antitoxin

HicB-like antitoxin of toxin-antitoxin system

(3-127)


Sequences

Toxin        


Download         Length: 61 a.a.        Molecular weight: 6675.81 Da        Isoelectric Point: 10.6643

>T283468 WP_011103638.1 NZ_CP126992:c4392833-4392651 [Pseudomonas syringae pv. antirrhini str. 126]
VQSRQLVKELEADGWVLDRVTGSHHMFKHPEKSQTVPVPHPKKDLPLGTVKAIRKLAGLA

Download         Length: 183 bp

Antitoxin


Download         Length: 135 a.a.        Molecular weight: 14386.41 Da        Isoelectric Point: 4.7182

>AT283468 WP_057418502.1 NZ_CP126992:c4392615-4392211 [Pseudomonas syringae pv. antirrhini str. 126]
MKYPICIEWGDETTAFGIQIPDIPGAITAGDTFEEAHAAAVEIAHIMLQEIAASGGSIPKVGTVAEHAKNPDFSGMGWGM
LEIDVTPYLGKTEKVNVTLPGFVIRQIDSYVRDHSIKSRSTFLADAALEKLGRA

Download         Length: 405 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB Q886E5

Antitoxin

Source ID Structure

References