Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 1410262..1410885 Replicon chromosome
Accession NZ_CP126975
Organism Gallibacterium anatis strain BJF12

Toxin (Protein)


Gene name relE Uniprot ID F4HF99
Locus tag QP018_RS06745 Protein ID WP_013746939.1
Coordinates 1410262..1410549 (-) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag QP018_RS06750 Protein ID WP_285097391.1
Coordinates 1410559..1410885 (-) Length 109 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QP018_RS06715 (QP018_06715) 1405539..1406465 + 927 WP_285092650.1 phosphoserine phosphatase -
QP018_RS06720 (QP018_06720) 1406478..1406969 + 492 WP_285092649.1 YajQ family cyclic di-GMP-binding protein -
QP018_RS06725 (QP018_06725) 1406991..1407158 + 168 WP_018345760.1 DUF5363 family protein -
QP018_RS06730 (QP018_06730) 1407243..1409258 + 2016 WP_052115960.1 NAD-dependent DNA ligase LigA -
QP018_RS06735 (QP018_06735) 1409461..1409727 + 267 WP_039135859.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein -
QP018_RS06740 (QP018_06740) 1409727..1410080 + 354 WP_039135860.1 type II toxin-antitoxin system PemK/MazF family toxin -
QP018_RS06745 (QP018_06745) 1410262..1410549 - 288 WP_013746939.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QP018_RS06750 (QP018_06750) 1410559..1410885 - 327 WP_285097391.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
QP018_RS06755 (QP018_06755) 1410984..1411244 - 261 WP_080735137.1 DUF1778 domain-containing protein -
QP018_RS06760 (QP018_06760) 1411386..1412489 - 1104 WP_285092647.1 porin -
QP018_RS06765 (QP018_06765) 1413256..1414311 + 1056 WP_285092818.1 porin -
QP018_RS06770 (QP018_06770) 1414617..1415693 - 1077 WP_285092819.1 porin -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-87)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(27-91)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11026.94 Da        Isoelectric Point: 10.4262

>T283432 WP_013746939.1 NZ_CP126975:c1410549-1410262 [Gallibacterium anatis]
MAYAIKVHSDFVAELNKLDSTIKNQLRKKLEKVVHNPHIPKNRLSGELHNCYKIKLRKAGVRLVYQVNDDEIYILLLTVG
KREAKQVYNTALNRV

Download         Length: 288 bp

Antitoxin


Download         Length: 109 a.a.        Molecular weight: 12381.25 Da        Isoelectric Point: 5.1351

>AT283432 WP_285097391.1 NZ_CP126975:c1410885-1410559 [Gallibacterium anatis]
MKNQQNQAAVIAFVLRLFYYYSKGGLMANLNIRIDDTIKQRAFLAFDNLGINPSEAIRTFLTYVADTGRMPIKQIIVSDE
DTELYEVVKKRLNEPEKITATTLDELFS

Download         Length: 327 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB F4HF99

Antitoxin

Source ID Structure

References