Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 574025..574445 Replicon chromosome
Accession NZ_CP126975
Organism Gallibacterium anatis strain BJF12

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag QP018_RS02725 Protein ID WP_285093661.1
Coordinates 574025..574159 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag QP018_RS02730 Protein ID WP_039081122.1
Coordinates 574161..574445 (+) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QP018_RS02710 (QP018_02710) 569594..570094 + 501 WP_285093628.1 DUF3158 family protein -
QP018_RS02715 (QP018_02715) 570468..572426 + 1959 WP_285093630.1 DNA topoisomerase III -
QP018_RS02720 (QP018_02720) 573319..573837 - 519 WP_285093631.1 hypothetical protein -
QP018_RS02725 (QP018_02725) 574025..574159 + 135 WP_285093661.1 hypothetical protein Toxin
QP018_RS02730 (QP018_02730) 574161..574445 + 285 WP_039081122.1 putative addiction module antidote protein Antitoxin
QP018_RS02735 (QP018_02735) 574847..575269 + 423 WP_018347289.1 hypothetical protein -
QP018_RS02740 (QP018_02740) 575373..575897 + 525 WP_039145119.1 hypothetical protein -
QP018_RS02745 (QP018_02745) 575965..576432 + 468 WP_285093633.1 hypothetical protein -
QP018_RS02750 (QP018_02750) 577032..577559 + 528 WP_285093634.1 STY4534 family ICE replication protein -
QP018_RS02755 (QP018_02755) 577638..577901 + 264 WP_285093635.1 hypothetical protein -
QP018_RS02760 (QP018_02760) 578037..578906 + 870 WP_013745189.1 SPFH domain-containing protein -
QP018_RS02765 (QP018_02765) 579140..579445 + 306 WP_013745187.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 562105..619543 57438


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(3-43)

Antitoxin

Uncharacterized protein HI1420

(4-91)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4776.62 Da        Isoelectric Point: 10.0582

>T283430 WP_285093661.1 NZ_CP126975:574025-574159 [Gallibacterium anatis]
VNKGYRIYLKNQNGVIVILLCGGDKSTQKADIEKAKSLAKELGV

Download         Length: 135 bp

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10527.05 Da        Isoelectric Point: 4.8255

>AT283430 WP_039081122.1 NZ_CP126975:574161-574445 [Gallibacterium anatis]
MVEKLHDFDMSEHLRTEEEIQLYLNEILAEGDVNLLLSALGDIAKARNMSQIAREVGVTREGLYKALSGQGNPTFATVFK
VMQALNLNLEVRHA

Download         Length: 285 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References