Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1876383..1876528 Replicon chromosome
Accession NZ_CP126974
Organism Klebsiella pneumoniae subsp. pneumoniae strain 111-2

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1876419..1876521 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1876383..1876528 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QPX97_RS09025 (QPX97_09025) 1871513..1873573 + 2061 WP_004151449.1 oligopeptidase B -
QPX97_RS09030 (QPX97_09030) 1873577..1874236 - 660 WP_002911407.1 exodeoxyribonuclease X -
QPX97_RS09035 (QPX97_09035) 1874315..1874545 - 231 WP_002911406.1 DNA polymerase III subunit theta -
QPX97_RS09040 (QPX97_09040) 1874658..1875032 + 375 WP_004151448.1 CopC domain-containing protein YobA -
QPX97_RS09045 (QPX97_09045) 1875036..1875905 + 870 WP_048331959.1 copper homeostasis membrane protein CopD -
QPX97_RS09050 (QPX97_09050) 1875922..1876260 + 339 WP_016529031.1 YebY family protein -
- 1876383..1876528 - 146 - - Antitoxin
- 1876419..1876521 + 103 - - Toxin
QPX97_RS09055 (QPX97_09055) 1876897..1877040 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
QPX97_RS09060 (QPX97_09060) 1877145..1878113 - 969 WP_074185275.1 VirK/YbjX family protein -
QPX97_RS09065 (QPX97_09065) 1878270..1878923 + 654 WP_032447686.1 protein-serine/threonine phosphatase -
QPX97_RS09070 (QPX97_09070) 1878920..1879111 - 192 WP_002911395.1 YebW family protein -
QPX97_RS09075 (QPX97_09075) 1879209..1879448 - 240 WP_002911393.1 YebV family protein -
QPX97_RS09080 (QPX97_09080) 1879564..1880997 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T283420 NZ_CP126974:1876419-1876521 [Klebsiella pneumoniae subsp. pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT283420 NZ_CP126974:c1876528-1876383 [Klebsiella pneumoniae subsp. pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References