Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2223387..2223658 | Replicon | chromosome |
| Accession | NC_018661 | ||
| Organism | Escherichia coli O104:H4 str. 2009EL-2071 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2223517..2223620 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2223387..2223658 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| O3O_RS11130 | 2219942..2220604 | - | 663 | WP_000944256.1 | exodeoxyribonuclease X | - |
| O3O_RS11135 | 2220628..2221284 | - | 657 | WP_000011658.1 | carbon-nitrogen hydrolase family protein | - |
| O3O_RS11140 | 2221386..2221616 | - | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| O3O_RS11145 | 2221755..2222129 | + | 375 | WP_000204699.1 | CopC domain-containing protein YobA | - |
| O3O_RS11150 | 2222133..2223005 | + | 873 | WP_000879280.1 | copper homeostasis membrane protein CopD | - |
| O3O_RS11155 | 2223018..2223359 | + | 342 | WP_000976472.1 | YebY family protein | - |
| - | 2223387..2223658 | - | 272 | - | - | Antitoxin |
| - | 2223517..2223620 | + | 104 | - | - | Toxin |
| O3O_RS11165 | 2223755..2224411 | + | 657 | WP_000812712.1 | protein-serine/threonine phosphatase | - |
| O3O_RS11170 | 2224412..2224603 | - | 192 | WP_001296140.1 | YebW family protein | - |
| O3O_RS11175 | 2224708..2224944 | - | 237 | WP_001295499.1 | DUF1480 family protein | - |
| O3O_RS11180 | 2225062..2226501 | - | 1440 | WP_000057022.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | - | 2145643..2239497 | 93854 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T28341 NC_018661:2223517-2223620 [Escherichia coli O104:H4 str. 2009EL-2071]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT
Antitoxin
Download Length: 272 bp
>AT28341 NC_018661:c2223658-2223387 [Escherichia coli O104:H4 str. 2009EL-2071]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
