Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-DinJ
Location 1844165..1844718 Replicon chromosome
Accession NZ_CP126958
Organism Aerococcus sp. UMB0080

Toxin (Protein)


Gene name relE Uniprot ID A0A2I1L771
Locus tag CJ190_RS08375 Protein ID WP_070598393.1
Coordinates 1844440..1844718 (+) Length 93 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A2I1L768
Locus tag CJ190_RS08370 Protein ID WP_070598390.1
Coordinates 1844165..1844440 (+) Length 92 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CJ190_RS08350 (CJ190_008350) 1841220..1842347 + 1128 WP_070598382.1 restriction endonuclease subunit S -
CJ190_RS08355 (CJ190_008355) 1842399..1842653 - 255 WP_070598384.1 Txe/YoeB family addiction module toxin -
CJ190_RS08360 (CJ190_008360) 1842653..1842898 - 246 WP_070598386.1 type II toxin-antitoxin system prevent-host-death family antitoxin -
CJ190_RS08365 (CJ190_008365) 1842953..1843873 - 921 WP_070598388.1 site-specific integrase -
CJ190_RS08370 (CJ190_008370) 1844165..1844440 + 276 WP_070598390.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
CJ190_RS08375 (CJ190_008375) 1844440..1844718 + 279 WP_070598393.1 type II toxin-antitoxin system YafQ family toxin Toxin
CJ190_RS08380 (CJ190_008380) 1844958..1845578 - 621 WP_070598395.1 restriction endonuclease subunit S -
CJ190_RS08385 (CJ190_008385) 1845578..1846489 - 912 Protein_1600 type I restriction-modification system subunit M -
CJ190_RS08390 (CJ190_008390) 1846566..1848059 - 1494 WP_101562046.1 recombinase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element erm(A) - 1803030..1940282 137252


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(1-90)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(3-87)


Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10947.78 Da        Isoelectric Point: 9.3100

>T283404 WP_070598393.1 NZ_CP126958:1844440-1844718 [Aerococcus sp. UMB0080]
MYKVKFTNAYKKSYKRMFKRGVDLSLLDEVVDNLRRGIQLDPRYKNHMLKGKFSGYFECHIKPDWLLIYLIEDDILTLTL
IDTGSHSDLFNL

Download         Length: 279 bp

Antitoxin


Download         Length: 92 a.a.        Molecular weight: 10104.54 Da        Isoelectric Point: 4.8004

>AT283404 WP_070598390.1 NZ_CP126958:1844165-1844440 [Aerococcus sp. UMB0080]
VATSPTQIRIDAKVKSEANELFNELGIDMSSAVNMFLRQCILRGGLPFSVELPRFNEATLNAMAEARRVSRDPDTPSYSS
MEELKKALLSE

Download         Length: 276 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I1L771

Antitoxin

Source ID Structure
AlphaFold DB A0A2I1L768

References