Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2297528..2297796 Replicon chromosome
Accession NZ_CP126942
Organism Escherichia coli O1:K1:H7 strain APEC E18006

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2297656..2297758 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2297528..2297796 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QQA29_RS11230 2294082..2294744 - 663 WP_000944256.1 exodeoxyribonuclease X -
QQA29_RS11235 2294767..2295423 - 657 WP_000011664.1 carbon-nitrogen hydrolase family protein YobB -
QQA29_RS11240 2295525..2295755 - 231 WP_000916763.1 DNA polymerase III subunit theta -
QQA29_RS11245 2295894..2296268 + 375 WP_000168747.1 CopC domain-containing protein YobA -
QQA29_RS11250 2296272..2297144 + 873 WP_000879320.1 copper homeostasis membrane protein CopD -
QQA29_RS11255 2297157..2297498 + 342 WP_000984819.1 YebY family protein -
- 2297528..2297796 - 269 - - Antitoxin
- 2297656..2297758 + 103 - - Toxin
QQA29_RS11260 2297893..2298549 + 657 WP_000812741.1 protein-serine/threonine phosphatase -
QQA29_RS11265 2298550..2298741 - 192 WP_001296140.1 YebW family protein -
QQA29_RS11270 2298846..2299082 - 237 WP_001295499.1 YebV family protein -
QQA29_RS11275 2299200..2300639 - 1440 WP_001350670.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T283204 NZ_CP126942:2297656-2297758 [Escherichia coli O1:K1:H7]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT283204 NZ_CP126942:c2297796-2297528 [Escherichia coli O1:K1:H7]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References