Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2343547..2343815 Replicon chromosome
Accession NZ_CP126940
Organism Escherichia coli O2:K1:H7 strain APEC E18055

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2343675..2343777 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2343547..2343815 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QQA30_RS11480 2340101..2340763 - 663 WP_000944256.1 exodeoxyribonuclease X -
QQA30_RS11485 2340786..2341442 - 657 WP_000011664.1 carbon-nitrogen hydrolase family protein YobB -
QQA30_RS11490 2341544..2341774 - 231 WP_000916763.1 DNA polymerase III subunit theta -
QQA30_RS11495 2341913..2342287 + 375 WP_000168747.1 CopC domain-containing protein YobA -
QQA30_RS11500 2342291..2343163 + 873 WP_000879320.1 copper homeostasis membrane protein CopD -
QQA30_RS11505 2343176..2343517 + 342 WP_000984819.1 YebY family protein -
- 2343547..2343815 - 269 - - Antitoxin
- 2343675..2343777 + 103 - - Toxin
QQA30_RS11510 2343912..2344568 + 657 WP_000812741.1 protein-serine/threonine phosphatase -
QQA30_RS11515 2344569..2344760 - 192 WP_001296140.1 YebW family protein -
QQA30_RS11520 2344865..2345101 - 237 WP_001295499.1 YebV family protein -
QQA30_RS11525 2345219..2346658 - 1440 WP_001350670.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T283175 NZ_CP126940:2343675-2343777 [Escherichia coli O2:K1:H7]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT283175 NZ_CP126940:c2343815-2343547 [Escherichia coli O2:K1:H7]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References