Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2172145..2172413 Replicon chromosome
Accession NZ_CP126937
Organism Escherichia coli O2:K1:H4 strain APEC E19019

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2172273..2172375 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2172145..2172413 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QQA31_RS10445 2168699..2169361 - 663 WP_000944256.1 exodeoxyribonuclease X -
QQA31_RS10450 2169384..2170040 - 657 WP_000011664.1 carbon-nitrogen hydrolase family protein YobB -
QQA31_RS10455 2170142..2170372 - 231 WP_000916763.1 DNA polymerase III subunit theta -
QQA31_RS10460 2170511..2170885 + 375 WP_000168747.1 CopC domain-containing protein YobA -
QQA31_RS10465 2170889..2171761 + 873 WP_000879320.1 copper homeostasis membrane protein CopD -
QQA31_RS10470 2171774..2172115 + 342 WP_000984819.1 YebY family protein -
- 2172145..2172413 - 269 - - Antitoxin
- 2172273..2172375 + 103 - - Toxin
QQA31_RS10475 2172510..2173166 + 657 WP_000812741.1 protein-serine/threonine phosphatase -
QQA31_RS10480 2173167..2173358 - 192 WP_001296140.1 YebW family protein -
QQA31_RS10485 2173463..2173699 - 237 WP_001295499.1 YebV family protein -
QQA31_RS10490 2173817..2175256 - 1440 WP_001350670.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T283152 NZ_CP126937:2172273-2172375 [Escherichia coli O2:K1:H4]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT283152 NZ_CP126937:c2172413-2172145 [Escherichia coli O2:K1:H4]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References