Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2225058..2225329 | Replicon | chromosome |
| Accession | NC_018658 | ||
| Organism | Escherichia coli O104:H4 str. 2011C-3493 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2225188..2225291 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2225058..2225329 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| O3K_RS10765 | 2221613..2222275 | - | 663 | WP_000944256.1 | exodeoxyribonuclease X | - |
| O3K_RS10770 | 2222299..2222955 | - | 657 | WP_000011658.1 | carbon-nitrogen hydrolase family protein | - |
| O3K_RS10775 | 2223057..2223287 | - | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| O3K_RS10780 | 2223426..2223800 | + | 375 | WP_000204699.1 | CopC domain-containing protein YobA | - |
| O3K_RS10785 | 2223804..2224676 | + | 873 | WP_000879280.1 | copper homeostasis membrane protein CopD | - |
| O3K_RS10790 | 2224689..2225030 | + | 342 | WP_000976472.1 | YebY family protein | - |
| - | 2225058..2225329 | - | 272 | - | - | Antitoxin |
| - | 2225188..2225291 | + | 104 | - | - | Toxin |
| O3K_RS10795 | 2225426..2226082 | + | 657 | WP_000812712.1 | protein-serine/threonine phosphatase | - |
| O3K_RS10800 | 2226083..2226274 | - | 192 | WP_001296140.1 | YebW family protein | - |
| O3K_RS10805 | 2226379..2226615 | - | 237 | WP_001295499.1 | DUF1480 family protein | - |
| O3K_RS10810 | 2226733..2228172 | - | 1440 | WP_000057022.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | - | 2148635..2241168 | 92533 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T28313 NC_018658:2225188-2225291 [Escherichia coli O104:H4 str. 2011C-3493]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT
Antitoxin
Download Length: 272 bp
>AT28313 NC_018658:c2225329-2225058 [Escherichia coli O104:H4 str. 2011C-3493]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
