Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 1527217..1527451 | Replicon | chromosome |
| Accession | NZ_CP126934 | ||
| Organism | Escherichia coli O78:H4 strain APEC E19057 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 1527218..1527321 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 1527217..1527451 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| QQA26_RS07745 | 1524415..1525224 | + | 810 | WP_000166317.1 | recombination protein RecT | - |
| QQA26_RS07750 | 1525281..1525475 | + | 195 | WP_042853000.1 | type I toxin-antitoxin system endodeoxyribonuclease toxin RalR | - |
| QQA26_RS07755 | 1525468..1525656 | + | 189 | WP_001356607.1 | DUF1187 family protein | - |
| - | 1525474..1525652 | - | 179 | NuclAT_1 | - | - |
| - | 1525474..1525652 | - | 179 | NuclAT_1 | - | - |
| - | 1525474..1525652 | - | 179 | NuclAT_1 | - | - |
| - | 1525474..1525652 | - | 179 | NuclAT_1 | - | - |
| QQA26_RS07760 | 1525763..1526044 | + | 282 | WP_001311878.1 | excisionase | - |
| QQA26_RS07765 | 1526010..1527086 | + | 1077 | WP_001189091.1 | phage integrase Arm DNA-binding domain-containing protein | - |
| - | 1527217..1527451 | + | 235 | - | - | Antitoxin |
| - | 1527218..1527321 | - | 104 | - | - | Toxin |
| QQA26_RS07770 | 1527479..1527820 | - | 342 | WP_000976492.1 | YebY family protein | - |
| QQA26_RS07775 | 1527833..1528705 | - | 873 | WP_000879280.1 | copper homeostasis membrane protein CopD | - |
| QQA26_RS07780 | 1528709..1529083 | - | 375 | WP_069024793.1 | CopC domain-containing protein YobA | - |
| QQA26_RS07785 | 1529222..1529452 | + | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| QQA26_RS07790 | 1529554..1530210 | + | 657 | WP_000011658.1 | carbon-nitrogen hydrolase family protein YobB | - |
| QQA26_RS07795 | 1530234..1530896 | + | 663 | WP_000944256.1 | exodeoxyribonuclease X | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | - | 1475840..1532953 | 57113 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T283113 NZ_CP126934:c1527321-1527218 [Escherichia coli O78:H4]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
Antitoxin
Download Length: 235 bp
>AT283113 NZ_CP126934:1527217-1527451 [Escherichia coli O78:H4]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
