Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2427815..2428083 Replicon chromosome
Accession NZ_CP126926
Organism Escherichia coli O2:K1:H5 strain APEC E19035

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2427943..2428045 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2427815..2428083 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QQA32_RS11805 2424369..2425031 - 663 WP_000944256.1 exodeoxyribonuclease X -
QQA32_RS11810 2425054..2425710 - 657 WP_021512072.1 carbon-nitrogen hydrolase family protein YobB -
QQA32_RS11815 2425812..2426042 - 231 WP_000916763.1 DNA polymerase III subunit theta -
QQA32_RS11820 2426181..2426555 + 375 WP_000168747.1 CopC domain-containing protein YobA -
QQA32_RS11825 2426559..2427431 + 873 WP_000879320.1 copper homeostasis membrane protein CopD -
QQA32_RS11830 2427444..2427785 + 342 WP_000984819.1 YebY family protein -
- 2427815..2428083 - 269 - - Antitoxin
- 2427943..2428045 + 103 - - Toxin
QQA32_RS11835 2428180..2428836 + 657 Protein_2319 protein-serine/threonine phosphatase -
QQA32_RS11840 2428837..2429028 - 192 WP_001296140.1 YebW family protein -
QQA32_RS11845 2429133..2429369 - 237 WP_001295499.1 YebV family protein -
QQA32_RS11850 2429487..2430926 - 1440 WP_001350670.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T283021 NZ_CP126926:2427943-2428045 [Escherichia coli O2:K1:H5]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT283021 NZ_CP126926:c2428083-2427815 [Escherichia coli O2:K1:H5]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References