283015

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RelB
Location 1795071..1795630 Replicon chromosome
Accession NZ_CP126699
Organism Vibrio vulnificus strain VV2018

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag QPX65_RS23125 Protein ID WP_206625632.1
Coordinates 1795352..1795630 (+) Length 93 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A3Q0L0M2
Locus tag QPX65_RS23120 Protein ID WP_011082348.1
Coordinates 1795071..1795355 (+) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QPX65_RS23095 (QPX65_23095) 1790585..1791778 + 1194 WP_011082341.1 glycine C-acetyltransferase -
QPX65_RS23100 (QPX65_23100) 1791837..1792868 + 1032 WP_011082342.1 L-threonine 3-dehydrogenase -
QPX65_RS23105 (QPX65_23105) 1792948..1793448 - 501 WP_206625628.1 opioid growth factor receptor-related protein -
QPX65_RS23110 (QPX65_23110) 1793525..1793788 - 264 WP_206625630.1 hypothetical protein -
QPX65_RS23115 (QPX65_23115) 1794028..1794837 - 810 WP_108678046.1 SUMF1/EgtB/PvdO family nonheme iron enzyme -
QPX65_RS23120 (QPX65_23120) 1795071..1795355 + 285 WP_011082348.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
QPX65_RS23125 (QPX65_23125) 1795352..1795630 + 279 WP_206625632.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QPX65_RS23130 (QPX65_23130) 1795659..1795751 - 93 WP_206625655.1 DUF3265 domain-containing protein -
QPX65_RS23135 (QPX65_23135) 1795775..1797244 - 1470 WP_047111818.1 hypothetical protein -
QPX65_RS23140 (QPX65_23140) 1797401..1797796 - 396 WP_047111819.1 hypothetical protein -
QPX65_RS23145 (QPX65_23145) 1798078..1798404 + 327 WP_045620244.1 hypothetical protein -
QPX65_RS23150 (QPX65_23150) 1798391..1798792 + 402 WP_045620245.1 hypothetical protein -
QPX65_RS23155 (QPX65_23155) 1799501..1800016 - 516 WP_045619818.1 lipocalin family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(2-89)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(5-45)


Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10860.54 Da        Isoelectric Point: 4.2397

>T283015 WP_206625632.1 NZ_CP126699:1795352-1795630 [Vibrio vulnificus]
MILWEEESLNDREKIFEFLYDFNPDAAEKTDNLIEAKVENLLEQPLMGVQRDSILGRLLIIPEISMVISYWVEGDIIRVL
RVLHQKQKFPTD

Download         Length: 279 bp

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 11083.43 Da        Isoelectric Point: 9.2167

>AT283015 WP_011082348.1 NZ_CP126699:1795071-1795355 [Vibrio vulnificus]
MDTRIQFRVDEETKRLAQQMAESQGRTLSDACRELTEQLAEQQRKTLSHDAWLTEQVNLAFEKFDSGKSVFIEHQTAKSR
MEERKARIRNRGKQ

Download         Length: 285 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A3Q0L0M2

References