Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) sanaTA/AbiEii-DUF6088
Location 396076..397423 Replicon chromosome
Accession NZ_CP126699
Organism Vibrio vulnificus strain VV2018

Toxin (Protein)


Gene name sanaT Uniprot ID -
Locus tag QPX65_RS17290 Protein ID WP_285458264.1
Coordinates 396482..397423 (+) Length 314 a.a.

Antitoxin (Protein)


Gene name sanaA Uniprot ID A0A854GL31
Locus tag QPX65_RS17285 Protein ID WP_017422919.1
Coordinates 396076..396480 (+) Length 135 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QPX65_RS17265 (QPX65_17265) 391269..391727 + 459 WP_285458255.1 exoribonuclease R -
QPX65_RS17270 (QPX65_17270) 391917..392663 + 747 WP_256389597.1 carbon-nitrogen hydrolase family protein -
QPX65_RS17275 (QPX65_17275) 393162..393926 + 765 WP_285458258.1 nucleotidyltransferase domain-containing protein -
QPX65_RS17280 (QPX65_17280) 393982..395742 - 1761 WP_285458260.1 ABC transporter ATP-binding protein/permease -
QPX65_RS17285 (QPX65_17285) 396076..396480 + 405 WP_017422919.1 DUF6088 family protein Antitoxin
QPX65_RS17290 (QPX65_17290) 396482..397423 + 942 WP_285458264.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
QPX65_RS17295 (QPX65_17295) 397690..401511 + 3822 WP_285458266.1 anti-phage defense-associated sirtuin Dsr1 -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(33-300)

Antitoxin

Protein of unknown function DUF6088

(7-130)


Sequences

Toxin        


Download         Length: 314 a.a.        Molecular weight: 36201.58 Da        Isoelectric Point: 5.0683

>T283014 WP_285458264.1 NZ_CP126699:396482-397423 [Vibrio vulnificus]
MNALKQQFLEVSDALELGNPAIIEKDFWVVALLAELAKVSPEYHQMVFSGGTALAKSNVKILRMSEDVDIKLIPNQAFDE
LSRAKKKAIRKEWVNEIEQEITHSERFTVETRSVRDEYRYVEFELRYPQQFSQVPCLRPIIKLELIETIPLLDVESRSIQ
SLVAELYQQPHEVSSFDCVSVYATLVEKIISMLRRTMSVKRNTERSDDVALVRHIYDVHCITKLTMSELNSIDGLFKAVL
EEDIARFGNQHAEFVANPKQELQLGLKELEENPIFRQRFQDFVTPMVFNTEPHDFDTCFASFKRIAASLIEKI

Download         Length: 942 bp

Antitoxin


Download         Length: 135 a.a.        Molecular weight: 15115.43 Da        Isoelectric Point: 10.6258

>AT283014 WP_017422919.1 NZ_CP126699:396076-396480 [Vibrio vulnificus]
MTAVDRICQKIKRSRRYVFERKDFDGFASYDQIGRALRQLVQQGELMKLGYGLYTKARINSLTGKPMPTNPGGTDALVRE
ILKMKGVDFEMDSLSQQSLSGASTQIPSSVHYSWNPKQFNRKLVVGSRVLNLPS

Download         Length: 405 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A854GL31

References