Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | sanaTA/AbiEii-DUF6088 |
Location | 396076..397423 | Replicon | chromosome |
Accession | NZ_CP126699 | ||
Organism | Vibrio vulnificus strain VV2018 |
Toxin (Protein)
Gene name | sanaT | Uniprot ID | - |
Locus tag | QPX65_RS17290 | Protein ID | WP_285458264.1 |
Coordinates | 396482..397423 (+) | Length | 314 a.a. |
Antitoxin (Protein)
Gene name | sanaA | Uniprot ID | A0A854GL31 |
Locus tag | QPX65_RS17285 | Protein ID | WP_017422919.1 |
Coordinates | 396076..396480 (+) | Length | 135 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
QPX65_RS17265 (QPX65_17265) | 391269..391727 | + | 459 | WP_285458255.1 | exoribonuclease R | - |
QPX65_RS17270 (QPX65_17270) | 391917..392663 | + | 747 | WP_256389597.1 | carbon-nitrogen hydrolase family protein | - |
QPX65_RS17275 (QPX65_17275) | 393162..393926 | + | 765 | WP_285458258.1 | nucleotidyltransferase domain-containing protein | - |
QPX65_RS17280 (QPX65_17280) | 393982..395742 | - | 1761 | WP_285458260.1 | ABC transporter ATP-binding protein/permease | - |
QPX65_RS17285 (QPX65_17285) | 396076..396480 | + | 405 | WP_017422919.1 | DUF6088 family protein | Antitoxin |
QPX65_RS17290 (QPX65_17290) | 396482..397423 | + | 942 | WP_285458264.1 | nucleotidyl transferase AbiEii/AbiGii toxin family protein | Toxin |
QPX65_RS17295 (QPX65_17295) | 397690..401511 | + | 3822 | WP_285458266.1 | anti-phage defense-associated sirtuin Dsr1 | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 314 a.a. Molecular weight: 36201.58 Da Isoelectric Point: 5.0683
>T283014 WP_285458264.1 NZ_CP126699:396482-397423 [Vibrio vulnificus]
MNALKQQFLEVSDALELGNPAIIEKDFWVVALLAELAKVSPEYHQMVFSGGTALAKSNVKILRMSEDVDIKLIPNQAFDE
LSRAKKKAIRKEWVNEIEQEITHSERFTVETRSVRDEYRYVEFELRYPQQFSQVPCLRPIIKLELIETIPLLDVESRSIQ
SLVAELYQQPHEVSSFDCVSVYATLVEKIISMLRRTMSVKRNTERSDDVALVRHIYDVHCITKLTMSELNSIDGLFKAVL
EEDIARFGNQHAEFVANPKQELQLGLKELEENPIFRQRFQDFVTPMVFNTEPHDFDTCFASFKRIAASLIEKI
MNALKQQFLEVSDALELGNPAIIEKDFWVVALLAELAKVSPEYHQMVFSGGTALAKSNVKILRMSEDVDIKLIPNQAFDE
LSRAKKKAIRKEWVNEIEQEITHSERFTVETRSVRDEYRYVEFELRYPQQFSQVPCLRPIIKLELIETIPLLDVESRSIQ
SLVAELYQQPHEVSSFDCVSVYATLVEKIISMLRRTMSVKRNTERSDDVALVRHIYDVHCITKLTMSELNSIDGLFKAVL
EEDIARFGNQHAEFVANPKQELQLGLKELEENPIFRQRFQDFVTPMVFNTEPHDFDTCFASFKRIAASLIEKI
Download Length: 942 bp
Antitoxin
Download Length: 135 a.a. Molecular weight: 15115.43 Da Isoelectric Point: 10.6258
>AT283014 WP_017422919.1 NZ_CP126699:396076-396480 [Vibrio vulnificus]
MTAVDRICQKIKRSRRYVFERKDFDGFASYDQIGRALRQLVQQGELMKLGYGLYTKARINSLTGKPMPTNPGGTDALVRE
ILKMKGVDFEMDSLSQQSLSGASTQIPSSVHYSWNPKQFNRKLVVGSRVLNLPS
MTAVDRICQKIKRSRRYVFERKDFDGFASYDQIGRALRQLVQQGELMKLGYGLYTKARINSLTGKPMPTNPGGTDALVRE
ILKMKGVDFEMDSLSQQSLSGASTQIPSSVHYSWNPKQFNRKLVVGSRVLNLPS
Download Length: 405 bp
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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