Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vagCD/VapC-VagC
Location 294672..295315 Replicon plasmid unnamed1
Accession NZ_CP126682
Organism Pantoea agglomerans strain FL1

Toxin (Protein)


Gene name vagD Uniprot ID -
Locus tag QPJ96_RS20160 Protein ID WP_161736537.1
Coordinates 294899..295315 (+) Length 139 a.a.

Antitoxin (Protein)


Gene name vagC Uniprot ID -
Locus tag QPJ96_RS20155 Protein ID WP_110332107.1
Coordinates 294672..294902 (+) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QPJ96_RS20140 (QPJ96_20140) 290362..291486 + 1125 WP_253417939.1 ATP-grasp domain-containing protein -
QPJ96_RS20145 (QPJ96_20145) 291636..292871 + 1236 WP_285088483.1 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme -
QPJ96_RS20150 (QPJ96_20150) 292849..294147 + 1299 WP_285088485.1 NtaA/DmoA family FMN-dependent monooxygenase -
QPJ96_RS20155 (QPJ96_20155) 294672..294902 + 231 WP_110332107.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
QPJ96_RS20160 (QPJ96_20160) 294899..295315 + 417 WP_161736537.1 type II toxin-antitoxin system VapC family toxin Toxin
QPJ96_RS20165 (QPJ96_20165) 296271..296564 - 294 WP_285088488.1 DUF1493 family protein -
QPJ96_RS20170 (QPJ96_20170) 296558..297016 - 459 WP_285088857.1 hypothetical protein -
QPJ96_RS20175 (QPJ96_20175) 297164..297763 - 600 WP_161736539.1 DUF1173 family protein -
QPJ96_RS20180 (QPJ96_20180) 298138..298458 - 321 WP_161736540.1 hypothetical protein -
QPJ96_RS20185 (QPJ96_20185) 298574..299269 - 696 WP_161736541.1 B3/4 domain-containing protein -
QPJ96_RS20190 (QPJ96_20190) 299313..299915 + 603 WP_161736542.1 helix-turn-helix transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - pla / iroN 1..504646 504646


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-129)

Antitoxin

SpoVT-AbrB domain

(7-42)


Sequences

Toxin        


Download         Length: 139 a.a.        Molecular weight: 15045.26 Da        Isoelectric Point: 6.7031

>T283009 WP_161736537.1 NZ_CP126682:294899-295315 [Pantoea agglomerans]
VNTTYMLDTCICSFIMREQPEAVLKRLEQAVMRGHRIVVSAITYSEMRFGATGPKASPRHAQLVDAFCARLDAVLPWDRA
AVDATTEIKVALRQAGTSIGPNDTAIAGHAISAGAVLVTNNTREFARVPDLALEDWVY

Download         Length: 417 bp

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8785.89 Da        Isoelectric Point: 4.3775

>AT283009 WP_110332107.1 NZ_CP126682:294672-294902 [Pantoea agglomerans]
MRTVSIFKNGNNRAIRLPRDMDFEGVSELEIIREGDSIILRPARPTWGSYLELEKADPDFMAEREDVVSDEGRFNL

Download         Length: 231 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References