Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hipBA/HipA-HipB
Location 2087224..2088785 Replicon chromosome
Accession NZ_CP126681
Organism Pantoea agglomerans strain FL1

Toxin (Protein)


Gene name hipA Uniprot ID -
Locus tag QPJ96_RS09790 Protein ID WP_285085762.1
Coordinates 2087472..2088785 (+) Length 438 a.a.

Antitoxin (Protein)


Gene name hipB Uniprot ID -
Locus tag QPJ96_RS09785 Protein ID WP_161734780.1
Coordinates 2087224..2087472 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QPJ96_RS09765 (QPJ96_09765) 2082474..2084699 + 2226 WP_285085759.1 iron ABC transporter permease -
QPJ96_RS09770 (QPJ96_09770) 2084696..2085757 + 1062 WP_161734788.1 ABC transporter ATP-binding protein -
QPJ96_RS09775 (QPJ96_09775) 2085781..2086572 + 792 WP_285085760.1 inositol monophosphatase family protein -
QPJ96_RS09780 (QPJ96_09780) 2086606..2087043 - 438 WP_285085761.1 GNAT family N-acetyltransferase -
QPJ96_RS09785 (QPJ96_09785) 2087224..2087472 + 249 WP_161734780.1 type II toxin-antitoxin system antitoxin HipB Antitoxin
QPJ96_RS09790 (QPJ96_09790) 2087472..2088785 + 1314 WP_285085762.1 type II toxin-antitoxin system HipA family toxin Toxin
QPJ96_RS09795 (QPJ96_09795) 2088889..2089095 + 207 WP_099257387.1 type II toxin-antitoxin system MqsA family antitoxin -
QPJ96_RS09800 (QPJ96_09800) 2089136..2090023 - 888 WP_161734776.1 benzoate transporter -
QPJ96_RS09805 (QPJ96_09805) 2090451..2091833 + 1383 WP_285085763.1 M24 family metallopeptidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HipA, N-terminal subdomain 1

(4-102)

Antitoxin

Cro/C1-type helix-turn-helix domain

(12-65)


Sequences

Toxin        


Download         Length: 438 a.a.        Molecular weight: 49215.84 Da        Isoelectric Point: 9.1315

>T283005 WP_285085762.1 NZ_CP126681:2087472-2088785 [Pantoea agglomerans]
MQRLIAWMNGERVGVLTRQRNGAHEFQYDTGWLSNPLSRPLSLSLPLQVKAITSHAVINFFDNLLPDSPLIRDRIVARYQ
IKSRQPFDLLQEVGRDSVGATMLLPPDMPLPALQARYEVLDEARLESVLSAYQSDIPLGMLREETDFRISVAGAQEKTAL
LLTEEGWSIPAGATPTSHIIKLPIGEIKQPAATLDMRESVENEYLCLALVRALGIDVPQATIIRAGKMRALAVERFDRRW
SRDRTRLIRLPQEDFCQALGLPSSTKYASDGGPGIAEIMQILMGSSNAIEDRYRFMMFQVFQWLIGATDGHAKNFSLFIE
RGGSYRLTPFYDVISAYPVLGGTGLNRRALKLAMGLRATKGKKTEIDKIFPRHFIATAKSVSFDRDSLQQIFDFFVREFP
KAVVSVREALPADYPQHIADAIFSHSLIMLERLRHKE

Download         Length: 1314 bp

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9246.55 Da        Isoelectric Point: 5.6579

>AT283005 WP_161734780.1 NZ_CP126681:2087224-2087472 [Pantoea agglomerans]
MIYSPLQLANRLKLIRQRNGWTQSELAKKVGLKQATISHFENAPDTTSLATLFKLLQALEVSLDVVEKEEASAPQLHDED
AW

Download         Length: 249 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References