282969

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) spoIISABC/SpoIISA-SpoIISB
Location 1348596..1349515 Replicon chromosome
Accession NZ_CP126576
Organism Bacillus licheniformis strain CQMB003

Toxin (Protein)


Gene name spoIISA Uniprot ID T5HIF3
Locus tag QPK28_RS06840 Protein ID WP_003180879.1
Coordinates 1348769..1349515 (-) Length 249 a.a.

Antitoxin (Protein)


Gene name spoIISB Uniprot ID T5HT37
Locus tag QPK28_RS06835 Protein ID WP_003180877.1
Coordinates 1348596..1348769 (-) Length 58 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QPK28_RS06810 1344021..1345118 + 1098 WP_003180867.1 mannonate dehydratase -
QPK28_RS06815 1345094..1345942 + 849 WP_003180869.1 SDR family oxidoreductase -
QPK28_RS06820 1345969..1346982 + 1014 WP_011197810.1 zinc-binding alcohol dehydrogenase family protein -
QPK28_RS06825 1347035..1348306 + 1272 WP_011197811.1 MFS transporter -
QPK28_RS06830 1348369..1348500 - 132 WP_003180875.1 hypothetical protein -
QPK28_RS06835 1348596..1348769 - 174 WP_003180877.1 type II toxin-antitoxin system SpoIISB family antitoxin Antitoxin
QPK28_RS06840 1348769..1349515 - 747 WP_003180879.1 type II toxin-antitoxin system SpoIISA family toxin Toxin
QPK28_RS06845 1349626..1350624 - 999 WP_009328723.1 inorganic phosphate transporter -
QPK28_RS06850 1350637..1351254 - 618 WP_003180884.1 DUF47 domain-containing protein -
QPK28_RS06855 1351586..1353343 + 1758 WP_003180886.1 gamma-glutamyltransferase -
QPK28_RS06860 1353472..1354116 + 645 WP_009328721.1 YesL family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin SpoIISA, type II toxin-antitoxin system

(3-238)

Antitoxin

Antitoxin SpoIISB

(1-57)


Sequences

Toxin        


Download         Length: 249 a.a.        Molecular weight: 29391.80 Da        Isoelectric Point: 4.5367

>T282969 WP_003180879.1 NZ_CP126576:c1349515-1348769 [Bacillus licheniformis]
MLLFYQFLVWLIVLALALYVAAVWRFEKQLAEKTVAIRKTWYLLYVIGAVIYWTHDPQSIFTNPLHYLIVAVFFTLTDAF
IFLNAYFKKLGSSELATDTRMLLEENNDLLHTYQNRLKTFQYLLKNEPIHIYYGNIEAYAEGIEKLIKRFAEKMNISAAL
CEYNSEESKDHLLEHMENRFDVQEKLDRKDVYYEENGKMVLIPFSIHDFDYVMKLTSEDLVTEFDYLLFTSLTSIYDLLL
PNEEEGDD

Download         Length: 747 bp

Antitoxin


Download         Length: 58 a.a.        Molecular weight: 6945.04 Da        Isoelectric Point: 10.9186

>AT282969 WP_003180877.1 NZ_CP126576:c1348769-1348596 [Bacillus licheniformis]
MEPAFQQDQESVKKRLAFKMFKRQSKTNIAKYEVSPHTERIFRQNERLIGEYKRKKA

Download         Length: 174 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB T5HIF3

Antitoxin

Source ID Structure
AlphaFold DB T5HT37

References