Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) omega-epsilon-zeta/-
Location 645192..646771 Replicon chromosome
Accession NZ_CP126568
Organism Xanthomonas oryzae pv. oryzicola strain HB8

Toxin (Protein)


Gene name avrRxo1 Uniprot ID -
Locus tag QPJ94_RS02930 Protein ID WP_149621311.1
Coordinates 645192..646457 (+) Length 422 a.a.

Antitoxin (Protein)


Gene name arc1 Uniprot ID A0A0C5UZA4
Locus tag QPJ94_RS02935 Protein ID WP_044749828.1
Coordinates 646475..646771 (+) Length 99 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QPJ94_RS02915 641185..641550 - 366 WP_224229821.1 SymE family type I addiction module toxin -
QPJ94_RS02920 643262..644287 + 1026 Protein_552 hemagglutinin repeat-containing protein -
QPJ94_RS02925 644287..644817 + 531 Protein_553 IS30 family transposase -
QPJ94_RS02930 645192..646457 + 1266 WP_149621311.1 zeta toxin family type III secretion system effector XopAJ/AvrRxo1 Toxin
QPJ94_RS02935 646475..646771 + 297 WP_044749828.1 hypothetical protein Antitoxin
QPJ94_RS02940 646993..647259 + 267 Protein_556 transposase -
QPJ94_RS02945 647326..647751 - 426 Protein_557 integrase core domain-containing protein -
QPJ94_RS02950 647880..648921 + 1042 WP_284572425.1 IS3 family transposase -
QPJ94_RS02955 648951..649028 + 78 Protein_559 anti-sigma factor antagonist -
QPJ94_RS02960 649123..649298 + 176 Protein_560 HAD family hydrolase -
QPJ94_RS02965 649514..650266 - 753 WP_024712407.1 YceI family protein -
QPJ94_RS02970 650477..651067 - 591 WP_014504809.1 malonic semialdehyde reductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 640742..656702 15960
- inside IScluster/Tn - - 633565..648921 15356


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Zeta toxin domain

(149-291)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 422 a.a.        Molecular weight: 45201.81 Da        Isoelectric Point: 6.9140

>T282964 WP_149621311.1 NZ_CP126568:645192-646457 [Xanthomonas oryzae pv. oryzicola]
MKNKTDIAGIAGLSTSHVSFDDAESKSVLDGSTQSTPEYKFQTPLDQLPARPAGPKSSNTTDAYIHESLPHSVPIAGAST
SAVTHQQATQRKGTDEIYGLGSLPSAGPERWDYLANPGNWHPERRKLHEKLLDQARSSALTLAESLESDGCQPTLFALRG
NTATGKTRIATKKIPVLAAALKKTGGKGCVNPDVFKSSLAKSEAGAKIFSSAQVHSESSFLADRFEGGLRSQKTGSGAIA
SIVVDKRLSRAYEIDSYIQLAKETGRKVELCDIDAPLENSLVGVLQRKPEGEDPRPPYPVVSSGFVAVRSNRMYVIDRFI
ADPSLGNYRLFGTAEDGEKVMVATVIGGEFSVENAELYEKITSPQLSVTGDLADKVIDKELIDRLKNNIADPERAAKTQA
ALEKYSGKSWSAALAAHSELI

Download         Length: 1266 bp

Antitoxin


Download         Length: 99 a.a.        Molecular weight: 11327.83 Da        Isoelectric Point: 5.2138

>AT282964 WP_044749828.1 NZ_CP126568:646475-646771 [Xanthomonas oryzae pv. oryzicola]
MKTLTGADALEFHKKLKERNKALHASDLELALVHADAVGKERFDLEELEKICDTSDAGRLTDAKERHDIYERMYYVEYPN
VMTLKEFAHIVETLSSWS

Download         Length: 297 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A0C5UZA4

References