Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /RES-Xre
Location 2680685..2681576 Replicon chromosome
Accession NZ_CP126539
Organism Devosia sp. RR2S18

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag QOV41_RS13150 Protein ID WP_284577169.1
Coordinates 2680685..2681212 (-) Length 176 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag QOV41_RS13155 Protein ID WP_284577171.1
Coordinates 2681205..2681576 (-) Length 124 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QOV41_RS13115 (QOV41_13115) 2675899..2676054 + 156 WP_284577159.1 hypothetical protein -
QOV41_RS13120 (QOV41_13120) 2676275..2676460 - 186 WP_284577160.1 hypothetical protein -
QOV41_RS13125 (QOV41_13125) 2677136..2677285 - 150 WP_284577161.1 hypothetical protein -
QOV41_RS13130 (QOV41_13130) 2677412..2678707 + 1296 WP_284577163.1 GGDEF domain-containing protein -
QOV41_RS13135 (QOV41_13135) 2678704..2678907 - 204 WP_284577165.1 hypothetical protein -
QOV41_RS13140 (QOV41_13140) 2679193..2679690 + 498 WP_284577166.1 BA14K family protein -
QOV41_RS13145 (QOV41_13145) 2679979..2680125 - 147 WP_284577168.1 hypothetical protein -
QOV41_RS13150 (QOV41_13150) 2680685..2681212 - 528 WP_284577169.1 RES domain-containing protein Toxin
QOV41_RS13155 (QOV41_13155) 2681205..2681576 - 372 WP_284577171.1 DUF2384 domain-containing protein Antitoxin
QOV41_RS13160 (QOV41_13160) 2681827..2682210 - 384 WP_284577173.1 type II toxin-antitoxin system PemK/MazF family toxin -
QOV41_RS13165 (QOV41_13165) 2682687..2682938 - 252 Protein_2592 transposase domain-containing protein -
QOV41_RS13170 (QOV41_13170) 2683628..2683828 + 201 WP_284581326.1 hypothetical protein -
QOV41_RS13175 (QOV41_13175) 2684054..2684452 - 399 WP_284577175.1 type II toxin-antitoxin system VapC family toxin -
QOV41_RS13180 (QOV41_13180) 2684452..2684685 - 234 WP_284577177.1 type II toxin-antitoxin system VapB family antitoxin -
QOV41_RS13185 (QOV41_13185) 2684935..2685095 - 161 Protein_2596 ATP-binding protein -
QOV41_RS13190 (QOV41_13190) 2685369..2685542 + 174 Protein_2597 transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(11-164)

Antitoxin

Antitoxin Xre/MbcA/ParS-like, toxin-binding domain

(71-120)


Sequences

Toxin        


Download         Length: 176 a.a.        Molecular weight: 19347.95 Da        Isoelectric Point: 6.4822

>T282958 WP_284577169.1 NZ_CP126539:c2681212-2680685 [Devosia sp. RR2S18]
MPEGPAPPIILWRAYVPRWSYQPLSGEGAARFGGRWNPLGVPTIYAARELSTAWAEYNQGFVQHSALIAQLHLTGAYLPD
LTVATVLRQFGLEESIHQIEWRSDLDSGIVPATHTAYQRLVDAGADGVVYPSYMSPGGTCVALWRWNRPGQPRLEILDPE
GRMPKSPASWGPPKE

Download         Length: 528 bp

Antitoxin


Download         Length: 124 a.a.        Molecular weight: 13190.08 Da        Isoelectric Point: 9.5904

>AT282958 WP_284577171.1 NZ_CP126539:c2681576-2681205 [Devosia sp. RR2S18]
MQSQGLEIGATRFGDGNSPFLSAHRLSEQLGLHQSELARLIGIARNTLAAKSASRKVDAALSPIVRILAMAAEMAGDENR
AVIWFKHQPIPGWAGKTAYDLVGEGKSDRVLAYLEAVRSGVYA

Download         Length: 372 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References