Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) ykfI-yfjZ/CbtA-CbeA
Location 77520..78202 Replicon chromosome
Accession NZ_CP126536
Organism Citrobacter freundii strain CRNMS1

Toxin (Protein)


Gene name ykfI Uniprot ID -
Locus tag QOK75_RS00375 Protein ID WP_108168483.1
Coordinates 77520..77861 (-) Length 114 a.a.

Antitoxin (Protein)


Gene name yfjZ Uniprot ID -
Locus tag QOK75_RS00380 Protein ID WP_108168484.1
Coordinates 77882..78202 (-) Length 107 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QOK75_RS00355 (74198) 74198..74725 - 528 WP_134216361.1 hypothetical protein -
QOK75_RS00360 (74772) 74772..75431 - 660 WP_134216360.1 antiviral reverse transcriptase Drt3a -
QOK75_RS00365 (75455) 75455..76048 - 594 WP_258982657.1 SLATT domain-containing protein -
QOK75_RS00370 (76573) 76573..77406 - 834 WP_099530882.1 DUF4942 domain-containing protein -
QOK75_RS00375 (77520) 77520..77861 - 342 WP_108168483.1 TA system toxin CbtA family protein Toxin
QOK75_RS00380 (77882) 77882..78202 - 321 WP_108168484.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
QOK75_RS00385 (78221) 78221..78442 - 222 WP_108168485.1 DUF987 domain-containing protein -
QOK75_RS00390 (78452) 78452..78928 - 477 WP_108168486.1 RadC family protein -
QOK75_RS00395 (78944) 78944..79402 - 459 WP_108168487.1 antirestriction protein -
QOK75_RS00400 (79483) 79483..79719 - 237 WP_108168488.1 DUF905 domain-containing protein -
QOK75_RS00405 (79797) 79797..80207 - 411 WP_043082399.1 hypothetical protein -
QOK75_RS00410 (80293) 80293..80907 - 615 WP_108168489.1 hypothetical protein -
QOK75_RS00415 (80904) 80904..81608 - 705 WP_108168490.1 WYL domain-containing protein -
QOK75_RS00420 (81809) 81809..82642 - 834 WP_108168491.1 DUF932 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 71024..89179 18155


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(1-112)

Antitoxin

Antitoxin CbeA

(6-105)


Sequences

Toxin        


Download         Length: 114 a.a.        Molecular weight: 12956.85 Da        Isoelectric Point: 7.2015

>T282936 WP_108168483.1 NZ_CP126536:c77861-77520 [Citrobacter freundii]
MKPQPATTSRAAELYLSPVAVWQMLLTRLLEQHYGLTLNDTPFSDETVIQEHIDAGIMLADAVNFLVEKYELVRIDRKGF
SWQEQSPYLRAVDILRARQATGLLRQSRNNAVR

Download         Length: 342 bp

Antitoxin


Download         Length: 107 a.a.        Molecular weight: 12027.71 Da        Isoelectric Point: 6.9370

>AT282936 WP_108168484.1 NZ_CP126536:c78202-77882 [Citrobacter freundii]
MRSNITWGLQRDITPCMGARLVQEGNRLHYLADRASITGKFSDDECLKLDVVFPHFISRIESMLTTGELNPRHAHCITIY
HNGFTCEADTLGSCAYVYVVVYSTQR

Download         Length: 321 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References