282933

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) spoIISABC/SpoIISA-SpoIISB
Location 2268609..2269525 Replicon chromosome
Accession NZ_CP126534
Organism Bacillus inaquosorum strain BSY82

Toxin (Protein)


Gene name spoIISA Uniprot ID -
Locus tag QN218_RS11755 Protein ID WP_060398450.1
Coordinates 2268609..2269355 (+) Length 249 a.a.

Antitoxin (Protein)


Gene name spoIISB Uniprot ID G4NV07
Locus tag QN218_RS11760 Protein ID WP_003239095.1
Coordinates 2269355..2269525 (+) Length 57 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QN218_RS11730 2263694..2263839 - 146 Protein_2312 hypothetical protein -
QN218_RS11735 2263940..2264890 - 951 WP_060398452.1 ring-cleaving dioxygenase -
QN218_RS11740 2265276..2266592 + 1317 WP_060398451.1 serine/threonine exchanger -
QN218_RS11745 2266868..2267485 + 618 WP_003218470.1 DUF47 domain-containing protein -
QN218_RS11750 2267498..2268499 + 1002 WP_003239093.1 inorganic phosphate transporter -
QN218_RS11755 2268609..2269355 + 747 WP_060398450.1 toxin-antitoxin-antitoxin system toxin SpoIISA Toxin
QN218_RS11760 2269355..2269525 + 171 WP_003239095.1 three component toxin-antitoxin-antitoxin system antitoxin SpoIISB Antitoxin
QN218_RS11765 2269610..2269747 + 138 WP_119913750.1 three component toxin-antitoxin-antitoxin system antitoxin SpoIISC -
QN218_RS11770 2269784..2270677 - 894 WP_060398449.1 N-acetylmuramoyl-L-alanine amidase -
QN218_RS11775 2270690..2270953 - 264 WP_003239099.1 phage holin -
QN218_RS11780 2270966..2271235 - 270 WP_060398448.1 hemolysin XhlA family protein -
QN218_RS11785 2271288..2272127 - 840 WP_060398447.1 hypothetical protein -
QN218_RS11790 2272174..2272338 - 165 WP_019258164.1 XkdX family protein -
QN218_RS11795 2272335..2272664 - 330 WP_060398446.1 XkdW family protein -
QN218_RS11800 2272676..2274481 - 1806 WP_250620463.1 terminase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin SpoIISA, type II toxin-antitoxin system

(3-238)

Antitoxin

Antitoxin SpoIISB

(1-56)


Sequences

Toxin        


Download         Length: 249 a.a.        Molecular weight: 29097.57 Da        Isoelectric Point: 4.6191

>T282933 WP_060398450.1 NZ_CP126534:2268609-2269355 [Bacillus inaquosorum]
MLLFFQIMVWCVMAGLGLYVYATWRFEAKVKEKMSAIRKTWYLLFVLGAMVYWTYEPSSLFTHWERYLIVAVSFALIDAF
IFLSAYVKKLAGSELETDTREILEENNEMLHMYLNRLKTYQYLLKNEPIHVYYGSIDAYAEGIDKLLKTYADKMNLTASL
CHYSTQADKDRLTEHMDDPADVQNRLDRKDVYYDQYGKMVLIPFTIETQSYVIKLTSDSIVTEFDYLLFTSLTSIYDLVL
PIEEEGEG

Download         Length: 747 bp

Antitoxin


Download         Length: 57 a.a.        Molecular weight: 6555.59 Da        Isoelectric Point: 10.8401

>AT282933 WP_003239095.1 NZ_CP126534:2269355-2269525 [Bacillus inaquosorum]
MERAFQNGCEPRAAKPFKILKKRSTTSVASYQVSPHTARIFKENERLIDEYKRKKA

Download         Length: 171 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB G4NV07

References