282932

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) spoIISABC/SpoIISA-SpoIISB
Location 1352525..1353441 Replicon chromosome
Accession NZ_CP126530
Organism Bacillus halotolerans strain Tehuacan_S4

Toxin (Protein)


Gene name spoIISA Uniprot ID -
Locus tag QPL78_RS07055 Protein ID WP_284560536.1
Coordinates 1352695..1353441 (-) Length 249 a.a.

Antitoxin (Protein)


Gene name spoIISB Uniprot ID A0A7G7U9Y3
Locus tag QPL78_RS07050 Protein ID WP_024121090.1
Coordinates 1352525..1352695 (-) Length 57 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QPL78_RS07010 (QPL78_07010) 1348242..1348571 + 330 WP_268498207.1 XkdW family protein -
QPL78_RS07015 (QPL78_07015) 1348568..1348732 + 165 WP_185848046.1 XkdX family protein -
QPL78_RS07020 (QPL78_07020) 1348776..1349615 + 840 WP_284560534.1 phage portal protein -
QPL78_RS07025 (QPL78_07025) 1349671..1349940 + 270 WP_024121085.1 hemolysin XhlA family protein -
QPL78_RS07030 (QPL78_07030) 1349952..1350215 + 264 WP_024121086.1 phage holin -
QPL78_RS07035 (QPL78_07035) 1350228..1351124 + 897 WP_268498202.1 N-acetylmuramoyl-L-alanine amidase -
QPL78_RS07040 (QPL78_07040) 1351201..1352292 + 1092 WP_284560535.1 acyltransferase family protein -
QPL78_RS07045 (QPL78_07045) 1352289..1352441 - 153 WP_151174960.1 three component toxin-antitoxin-antitoxin system antitoxin SpoIISC -
QPL78_RS07050 (QPL78_07050) 1352525..1352695 - 171 WP_024121090.1 type II toxin-antitoxin system SpoIISB family antitoxin Antitoxin
QPL78_RS07055 (QPL78_07055) 1352695..1353441 - 747 WP_284560536.1 type II toxin-antitoxin system SpoIISA family toxin Toxin
QPL78_RS07060 (QPL78_07060) 1353551..1354552 - 1002 WP_024121092.1 inorganic phosphate transporter -
QPL78_RS07065 (QPL78_07065) 1354565..1355182 - 618 WP_010333926.1 DUF47 domain-containing protein -
QPL78_RS07070 (QPL78_07070) 1355458..1356774 - 1317 WP_284560537.1 serine/threonine exchanger -
QPL78_RS07075 (QPL78_07075) 1357169..1358119 + 951 WP_105990669.1 ring-cleaving dioxygenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin SpoIISA, type II toxin-antitoxin system

(3-238)

Antitoxin

Antitoxin SpoIISB

(1-56)


Sequences

Toxin        


Download         Length: 249 a.a.        Molecular weight: 29110.50 Da        Isoelectric Point: 4.4986

>T282932 WP_284560536.1 NZ_CP126530:c1353441-1352695 [Bacillus halotolerans]
MLLFFQIMVWCTMAALGLYVYATWRFEAKVKEKMSAIRKTWYLLFVFGAMIYWTYDPSSLFTNWERYVIVAVSFALIDAF
IFLSAYVKKLAGSELETDTREILEENNEMLHMYLDRLKTYQYLLKNEPIHVYYGSIEAYAEGIDKLLKTYADKMNLTASL
CHYSTQSDKDRLTEHMEDPADVQTRLDRKDVYYDQYGKVVLIPFTIETQSYVIKLTSDSIVTEFDYLLFTSLTSIYDLVL
PIEEEGEG

Download         Length: 747 bp

Antitoxin


Download         Length: 57 a.a.        Molecular weight: 6578.62 Da        Isoelectric Point: 10.9236

>AT282932 WP_024121090.1 NZ_CP126530:c1352695-1352525 [Bacillus halotolerans]
MENAFQNGCHPRAKKPFKILKKRSTTSVASYQVSPHTARIFKENERLIDEYKRKKA

Download         Length: 171 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A7G7U9Y3

References