Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /SpoIISA(toxin)
Location 2423067..2424045 Replicon chromosome
Accession NZ_CP126524
Organism Bacillus toyonensis strain Monterrey_S3

Toxin (Protein)


Gene name spoIISA Uniprot ID K0FNW8
Locus tag QPL83_RS14095 Protein ID WP_000155917.1
Coordinates 2423067..2423807 (+) Length 247 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID J8KE32
Locus tag QPL83_RS14100 Protein ID WP_000588713.1
Coordinates 2423920..2424045 (+) Length 42 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QPL83_RS14075 (QPL83_14075) 2418727..2419509 + 783 Protein_2370 class I SAM-dependent methyltransferase -
QPL83_RS14080 (QPL83_14080) 2419690..2421366 - 1677 WP_284555930.1 alpha-keto acid decarboxylase family protein -
QPL83_RS14085 (QPL83_14085) 2421493..2421975 + 483 WP_000191892.1 MarR family winged helix-turn-helix transcriptional regulator -
QPL83_RS14090 (QPL83_14090) 2422143..2422880 + 738 WP_000594132.1 2,3-diphosphoglycerate-dependent phosphoglycerate mutase -
QPL83_RS14095 (QPL83_14095) 2423067..2423807 + 741 WP_000155917.1 type II toxin-antitoxin system SpoIISA family toxin Toxin
QPL83_RS14100 (QPL83_14100) 2423920..2424045 + 126 WP_000588713.1 hypothetical protein Antitoxin
QPL83_RS14105 (QPL83_14105) 2424121..2424297 + 177 WP_000808012.1 stage II sporulation protein SB -
QPL83_RS14110 (QPL83_14110) 2424346..2424735 - 390 WP_000732294.1 YxeA family protein -
QPL83_RS14115 (QPL83_14115) 2424979..2426448 + 1470 WP_284555931.1 beta-Ala-His dipeptidase -
QPL83_RS14120 (QPL83_14120) 2426759..2427568 + 810 WP_000678381.1 papain-like cysteine protease family protein -
QPL83_RS14125 (QPL83_14125) 2427596..2428198 + 603 WP_284555932.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin SpoIISA, type II toxin-antitoxin system

(10-244)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 247 a.a.        Molecular weight: 28446.03 Da        Isoelectric Point: 7.3946

>T282928 WP_000155917.1 NZ_CP126524:2423067-2423807 [Bacillus toyonensis]
MTISNIRIGLFILAIVFVVLVFFYWRNEELYEEKKQRIRKTWYGLFITSVTVYFMIKGIDLTLWKNLLMFTAMVIFVDIS
FILTPNISEIWGAKFSDIGKTVQSIKRSLIASKARGEIYTNIIQNINPAAFGTMEWHTEEEYTKSLNTFLDSYGEKIGAK
IVVFEAANELNTGFRGIRSQFSITIPIEHIEQLNEQKAVQVENVGIIPAKIMNDVFIVIDGKKNSLQDRDFENVYNLTIH
HSYFSK

Download         Length: 741 bp

Antitoxin


Download         Length: 42 a.a.        Molecular weight: 4951.43 Da        Isoelectric Point: 4.1079

>AT282928 WP_000588713.1 NZ_CP126524:2423920-2424045 [Bacillus toyonensis]
VIKDYDNDFFKEENEDTTDFSLIKGDTLQQVEKLEEELKRK

Download         Length: 126 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB K0FNW8

Antitoxin

Source ID Structure
AlphaFold DB J8KE32

References